小RhoGTPase RhoC,但不是 RhoA,参与机械应力诱导的 CTGF 上调 RhoA 家族的小 GTPase 是关键的分子开关,参与细胞外环境和细胞骨架动力学发出的机械信号的转导。实验通过用 siRNA 沉默 RhoA、RhoC、Rac1 和 Cdc42 的表达,研究它们在机械应力诱导的 CTGF 上调中的作用。RhoA、RhoC 和 Rac1 的 SiRNA 有效且特异性...
使用微管蛋白作为蛋白负荷控制,静态(—)和拉伸(+)VIC 中 CTGF 产生的代表性蛋白质印迹结果(E)。 小RhoGTPase RhoC,但不是 RhoA,参与机械应力诱导的 CTGF 上调 RhoA 家族的小 GTPase 是关键的分子开关,参与细胞外环境和细胞骨架...
众所周知,Rho GTPase通过激活下游多种效应蛋白来调节细胞的生物学功能。RhoC作为Rho GTPase家族的重要成员,主要参与调节细胞骨架重组、细胞黏附与迁移、恶性肿瘤增殖、转移等生物学功能[6, 12-13]。RhoC高表达可促进结直肠癌细胞的增殖、侵袭...
RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells. Neoplasia . 2000; 2 (5):418–425.van Golen KL, Wu ZF, Qiao XT, Bao L, Merajver SD. RhoC GTPase overexpression modulates induction of angiogenic factors in breast cells. Neoplasia. 2000; 2 (5):418–425....
RhoA 家族的小 GTPase 是关键的分子开关,参与细胞外环境和细胞骨架动力学发出的机械信号的转导。实验通过用 siRNA 沉默 RhoA、RhoC、Rac1 和 Cdc42 的表达,研究它们在机械应力诱导的 CTGF 上调中的作用。RhoA、RhoC 和 Rac1 的 SiRNA 有效且特异性地沉默了它们的靶标(图2 A)。
别名:ARH 9; ARH9; ARHC; H9; MGC1448; MGC61427; Oncogene RHO H9; Ras homolog gene family member C; RAS related homolog 9; RHO C; Rho cDNA clone 9; Rho related GTP binding protein RhoC; Rho-related GTP-binding protein RhoC; rhoC; RhoC GTPase; RHOC_HUMAN; RHOH 9; RHOH9; Small GT...
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook AcronymDefinition RHOCRadiation Hardened Oversight Council(US DoD) RHOCReceding Horizon Optimal Control(algorithm; agriculture) RHOCRegional Home Ownership Center RHOCRoyal Highlanders of Canada ...
别名RhoC protein; RHOC; ARH9; ARHC; ARH 9; H9; MGC1448; MGC61427; Oncogene RHO H9; Ras homolog gene family member C; RAS related homolog 9; RHO C; Rho related GTP binding protein RhoC; RhoC GTPase; RHOH 9; RHOH9; Small GTP binding protein RhoC. ...
产品别名: RhoC protein; RHOC; ARH9; ARHC; ARH 9; H9; MGC1448; MGC61427; Oncogene RHO H9; Ras homolog gene family member C; RAS related homolog 9; RHO C; Rho related GTP binding protein RhoC; RhoC GTPase; RHOH 9; RHOH9; Small GTP binding protein RhoC. ...
Ridley AJ. RhoA, RhoB and RhoC have different roles in cancer cell migration. J Microsc. 2013;251:242-9.Ridley AJ. 2013. RhoA, RhoB and RhoC have different roles in cancer cell migration. J Microsc. 251:242-249.Ridley AJ. RhoA, RhoB and RhoC have different roles in cancer cell ...