Rhinovirus infections in infants suggest that early detection can prevent unnecessary treatmentRhinovirusRespiratoryHospitalizedInfluenza-like illnessBackground: Human rhinoviruses (hRV) are small, RNA viruses of the Picornaviridae family, which are divided into three subtypes (A, B, C). hRVs are ...
Respiratory syncytial virus is often thought of as the principal infectious pathogen for URIs in infants and young children, and there is increasing evidence that HRV also causes significant lower respiratory tract disease in this population.15 HRV spreads through the airway and infects the epithelial...
However, their role in low risk infants without an asthmatic predisposition is unknown. Knowing which healthy, low risk children are at increased risk for childhood wheezing after rhinovirus wheezing illness (RV‐WI) in infancy, might help in developing prevention and treatment strategies for ...
Human rhinovirus is responsible for causing 50% of common cold infections in infants and adults. It belongs to the picornavirus family of nonenveloped positive-strand RNA viruses. The RNA synthesis of rhinovirus is carried out by RNA-dependent RNA polymerase, also known as 3DPol. It catalyzes ...
1i, j). Finally, to elucidate if treatment with ICS would impact any of the observed responses in patients with asthma, we stratified them according to their baseline treatment (Supplementary Fig. 1). We have not found any major differences in expression of RIG-I inflammasome-related genes ...
Using nasal saline drops with bulb-syringe nostril aspiration, in infants with congestion and obstruction Discontinuing smoking or using alcohol Pharmacologic treatment includes the following: The combined effect of NSAIDs and antihistamines often relieves nasal obstruction. Oral decongestants (pseudoephed...
Respiratory tract infections (RTI) are a major cause of morbidity and mortality in humans. A large number of RTIs is caused by viruses, often resulting in more severe disease in infants, elderly and the immunocompromised. Upon viral infection, most individuals experience common cold-like symptoms...
While human rhinoviruses are generally considered upper respiratory viruses, there is a growing awareness that these viruses can cause infections in the lower respiratory tract as well, particularly for infants, the elderly, immunocompromised patients, and those with asthma.2 In fact, for immunocompromi...
Human respiratory viral infections: Current status and future prospects of nanotechnology-based approaches for prophylaxis and treatment ShilpaDawre,SaurabhMaru, inLife Sciences, 2021 2.2Human Rhinovirus HumanRhinovirus(HRVs) is a member of the virus familyPicornaviridae. The two strains of HRVs are ...
challenge.90Unfortunately, the study did not find any improvement in lung function, and mepolizumab did not prevent eosinophil activation. Furthermore, although symptoms were not different in the treatment arm, there was a significantly higher viral load in the treatment group, suggesting an antiviral...