The article discusses the management of rhinovirus in older patients. Topics cited include some signs and symptoms that older patients may experience, key reasons why some older patients are susceptible to infection such as impaired physiologic function and lower cellular immunity, and clinical features...
While the majority of replication was initially felt to be limited to the upper airway, a growing body of evidence suggests that HRVs can and frequently may replicate in the lower airways. This is likely to be more common among individuals with lower airway signs and symptoms and may contribut...
In most cases, rhinovirus leads to a short self-limiting illness. However, for asthmatics, the elderly and immunocompromised patients, rhinovirus infection can lead to life-threatening complications. This has spurred a consistent effort over recent decades to identify effective treatments and ...
These changes are associated with an increased number of asthma symptoms. Rhinovirus may produce lower airway dysfunction and trigger asthma exacerbations in 2 different ways, either directly by infecting the lower airways or indirectly by infecting the upper airways and stimulating inflammatory, ...
The best remedy for the common cold is resting and drinking plenty of fluids, although symptoms may be alleviated with over-the-counter medications.1 It’s important to know when to seek medical care, since a human rhinovirus infection can lead to complications for children, the elderly, and...
2 Because these symptoms may be present with a bacterial URI, it has been a challenge for clinicians to differentiate viral from bacterial causes. Now that agents specifically targeted to respiratory viruses have been developed and may become available, it has Role of Picornaviruses in VRI The ...
Rhinovirus and Coronavirus Infections Stephen B Greenberg M D 1 ABSTRACT Rhinoviruses and coronaviruses cause the majority of common colds and play a part in more serious respiratory illnesses that lead to increased morbidity and mortality Patients who are infants or elderly have asthma or chronic ...
Rhinovirus is a common cause of upper and lower respiratory tract infections in adults, especially among the elderly and immunocompromised. Nevertheless, its clinical characteristics and mortality risks have not been well described. A retrospective analysis on a prospective cohort was conduc...
The number of infectious HAV particles necessary to initiate an infection after ingestion may be very low, perhaps in some cases even single particles (Cliver, 1985). After ingestion, there is an incubation period of around six weeks before the onset of acute symptoms. However, the greater the...
Pleconaril, a viral capsid inhibitor, has been shown to reduce the RV viral load in respiratory secretions and in shortening of the duration of respiratory symptoms in adults with RV respiratory tract infections (Pevear et al., 2005). But, it is not licensed for use in the United Kingdom ...