anti-TNF or anti-IL1 therapy may indicate that the disease process in such patients may not be refractory to therapy but in fact is driven by a different cytokine, in this case IL6. We conclude that when faced with a JIA patient with apparent resistance to treatment...
Adverse Childhood Experiences (ACEs) such as witnessing violence in the home or neighborhood, parental incarceration, and racial or ethnic discrimination are associated with increased risk of chronic disease and poorer health in children and adults. Emerging data suggest an association between exposure to...
In South America the incidence of Paget’s disease of bone (PDB) is low and more than half of the cases published in the last 30 years come from Brazil and Argentina. The aim of this study was to describe the clinical and epidemiological characteristics of PDB in two institutions in Pernam...