History taking in rheumatology is the most important skill needed for proper handling of a patient with a rheumatological complaint. Obtaining a good history will help you to reach almost 90% of your diagnosis. However, history taking is mostly depending on experience and practice rather than ...
Armed immunocytokines and antibody–drug conjugates combine targeting specificity and effector functions of antibodies with the immunological effect of their payloads. Bispecific antibodies might treat rheumatic diseases by taking advantage of a variety of diverse antibody functions.This...
The treat-to-target (T2T) concept has improved outcomes for patients with diabetes, hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well-defined, relevant target, taking therapeutic steps, evaluating whether the targe
Control participants had no joint disease or history of inflammatory arthritis (and no affected first-degree relatives). Control individuals included coworkers at the University of Leeds (eg, academics, administrative workers, laboratory staff, cleaning staff) and people from the local community (eg,...
UCB is sharing two-year data from the Phase 4 C-VIEW study addressing a significant unmet need for axSpA patients with a history of acute anterior uveitis (AAU). AAU is the most common extra-articular manifestation in axSpA, affecting up to 40 percent of pa...
32 Additionally, given the long history of pain and opioid treatment, it is important to note that our results may not be generalizable to patients with CNCP who have just begun using opioids. There were missing data in our cohort, and a range of strategies was used to examine and impute ...
We found a high prevalence of ILTB that doubled with immunosuppression and that epidemiological history was an important relative risk. T. SPOT.TB showed low sensitivity and high specificity, and no superiority over TST. There was low agreement and little influence of immunosuppression on the result...
In this study, not all patients positive for IGRA tested positive for TST and vice versa. This indicated that performing only 1 test may result in false negative results, and higher rate of LTBI reactivation. For the patients at high risks or immunosuppression, a combination of history, physica...
Previously the pharmacist was responsible for contacting patients/parents and carers to remind them of overdue blood tests taking around 45 min a week. With VSM the PCC was identified as the best person to do this. On a weekly basis the pharmacist will access the TDM database and update a ...
The emergence of large language models (LLM) with remarkable performance such as ChatGPT, has led to an unprecedented uptake in the population, being the fastest-growing application in history1, and with the potential to transform various domains, including medicine2. A clear example of this burg...