Rheumatoid factor is a blood test that helps to diagnose rheumatoid arthritis, lupus, and sarcoidosis. Elevated test results, or high levels, indicate severe disease. Learn about the normal range for rheumatoid factor.
Rheumatoid Factor Test Results Receiving test results Results are normally available within a few business days of taking an RF test. They may be shared with you via phone, mail, or electronically. In some cases, doctors may wait to share the results of RF testing until other testing is comp...
The latex test revisited: rheumatoid factor testing in 8,287 rheumatic disease patients. Arthritis Rheum 1991;34:951-60.Wolfe F, Cathey MA, Roberts FK. The latex test revisited: rheumatoid factor testing in 8,287 rheumatic disease patients. Arthritis Rheum 1991; 34:951-960...
Rheumatoid factor (RF) immunoglobulins on the other hand, carry relatively modest somatic hypermutation numbers24,25. RF+B cells also show a distinctly different transcriptional profile compared to ACPA+B cells, with more innate-like pathways active25. RFs are composed primarily of IgM isotype, alth...
Clinical and demographic data, including age, sex, ethnicity, body mass index (BMI), smoking status, the numbers of tender and swollen joints, patient and evaluator global assessments, C-reactive protein (CRP, mg/L), and results for rheumatoid factor (RF, IU/mL) and anti-CCP (U/mL), ...
In competition-type immunoassays, rheumatoid factors bind to the assay antibody, preventing its reaction to the label reagent through steric-hindrance, thus generating false-positive results. If rheumatoid factors are suspected to cause interference, the patient’s history needs to be examined. It is...
The biotin-streptavidin ELISA proved to be more sensitive than a commercial latex agglutination test and similar in sensitivity to a screening slide-agglutination test using IgG-coated human erythrocytes. When sera that had had positive results in tube-dilution assays both with sensitized human ...
For each method, we implemented the model according to the original paper, trained it on our training dataset, and tested it on our prospective test dataset and external test dataset, respectively. To make the experimental results more convincing, we replicated each experiment five times. The ...
To assess the enrichment results of gene sets in the nuclear transcriptome microarray data. To evaluate if various pathways are enriched across distinct samples. The gene set ‘h.all.v7.4.symbols.gmt’ was acquired from the MSigDB database. GSVA was conducted on the RA dataset to assess the ...
Results Univariate quality control Subjects and patients: sex discrepancies were discovered in 19 subjects, 2 subjects had a missing value rate above 5%, and 5 subjects were found to be related: these subjects were removed from the analysis. A total of 26 subjects, predominantly RA patients, wer...