Pathogenesis of Rheumatoid Arthritis Rheumatoid arthritis (RA) is a chronic symmetric polyarticular joint disease that primarily affects the small joints of the hands and feet. The inflammatory process is characterized by infiltration of inflammatory cell...
Many types of cells are activated and transformed in rheumatoid synovium, thereby contributing to amplification of the disease process. The immune response in rheumatoid arthritis is probably initiated by an antigen, although there is some evidence that anticollagen antibodies develop in response to ...
Rheumatoid arthritis: cardiovascular manifestations, pathogenesis, and therapy. Rheumatoid Arthritis (RA) is a chronic progressive inflammatory joint disorder that affects 0.5% 1% of the general population. This review article discuss... W M. Mellana,W S. Aronow,C Palaniswamy,... - 《Current ...
Rheumatoid arthritis (RA) is traditionally considered to be a T-cell–mediated disease. Additional data have implicated T-cell–independent pathways in its pathogenesis, however, especially in late stages of the disease. 26,32 No one can reasonably dispute that RA is a disease involving immunologic...
类风湿关节炎RheumatoidArthritisRA 类风湿关节炎 RheumatoidArthritis(RA)郑州大学第一附属医院 ByRaoulDufy(1877-1953)Outline •Definitionandhistory•Prevalance•Etiology,pathogenesisandpathology•Clinicalfeatures•Laboratoryfindings•Imaging•Diagnosisanddifferentialdiagnosis•Management RA定义 •Anautoimmune...
Rheumatoid arthritis (RA) is a chronic and progressive inflammatory disorder, characterized by synovitis and severe joint destruction. Many mechanisms are considered to be implicated in the development and progression of the disease. It may be important to understand differences in the pathogenesis of ...
The cause of rheumatoid arthritis (RA) is unknown; however, extensive research has yielded great insight into its pathogenesis. Lymphocytes play a significant role, but a lesser role in the perpetuation of late disease. The rheumatoid synovium is composed primarily of fibroblasts and monocytes that ...
The PU.1– IL-9 axis in TH9 cells promotes RA Findings show a role for the PU.1–IL-9 axis in TH9 cells in the pathogenesis of RA. Holly Webster Research Highlights25 Sept 2024Nature Reviews Rheumatology Volume: 20, P: 667 Nature.com...
Kraan MC, Reece RJ, Smeets TJ, Veale DJ, Emery P, Tak PP: Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: implications for pathogenesis and evaluation of treatment. Arthritis... MC Kraan,RJ Reece,TJM Smeets,... - 《Arthritis & Rh...
Role of IL-17 in the Pathogenesis of Rheumatoid Arthritis Interleukin (IL)-17 (also known as IL-17A), the signature cytokine of the newly described T helper 17 (Th17) cell population, has been implicated in the pa... SL Gaffen - 《Current Rheumatology Reports》 被引量: 429发表: 2009年...