This study aimed to conduct a comprehensive systematic literature review and meta-analysis to assess the risk and outcomes of coronavirus disease 2019 (COVID-19) in patients with rheumatoid arthritis. A systematic search was performed across four electro
Rheumatoid arthritis (RA) not only has a physical and emotional toll but also has a substantial economic impact. This study aims to estimate the burden of catastrophic health expenditure (CHE) on households due to RA in Tamil Nadu, India. We conducted cross-sectional descriptive hospital-based ...
Extended report:Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from... Background In the IMAGEstudy, rituximab plus methotrexate (MTX) inhibited joint damage and improved clinical outcomes at 1 year in MTX-naïve...
Rheumatoid arthritis (RA), a chronic inflammatory disease affects up to 1% of the general population. Early diagnosis and treatment are limited by the absence of specific and reliable diagnostic/prognostic biomarkers. This study was carried out in 48 Tamil South Indian RA patients and 49 healthy ...
Techniques coupled with quantitative Polymerase Chain Reaction (qPCR) and High-Resolution Melting Analysis (HRMA) were used to screen CTLA-4 3’Untranslated Region (UTR) CT60 (A/G) rs3087243 Single Nucleotide Polymorphism (SNP) and their association with Rheumatoid Arthritis (RA) in the Indian ...
Significant dysregulation of NKG 2D, an activating receptor of natural killer and certain autoreactive T cells as well as its ligand major histocompatibility complex class I chain–related gene A ( MICA ) has been implicated in perpetuating the pathology of RA . Since the genetic polymorphism in ...
Introduction Rheumatoid arthritis ( RA ) is a clinically heterogeneous chronic inflammatory disorder characterized by synovitis leading to joint destruction. Both genetic and environmental factors are involved in the pathogenesis of RA . Significant dysregulation of NKG 2D, an activating receptor of natural...
P21 The inducible nitric oxide synthase (NOS2) gene promoter polymorphisms in rheumatoid arthritis patients in Tamil Nadu, South Indiadoi:10.1016/S0973-3698(09)60039-XMChristinaMaryandVSNegiandRTamouzaandSDOSIndian Journal of RheumatologyInducible nitric oxide synthase gene promoter polymorphism is ...
Mariaselvam, C. M.Fortier, C.Charron, D.Krishnamoorthy, R.Tamouza, R.Negi, V. S.HLA.Mariaselvam CM, Fortier C, Charron D, et al. HLA class II alleles influence rheumatoid arthritis susceptibility and autoantibody status in South Indian Tamil population. HLA 2016;88:253-258....
Translation and Validation of Tamil Version of Fatigue Severity Scale (FSS) in Individuals with Rheumatoid Arthritisdoi:10.1177/09733698241232849Background: Fatigue has a significant negative impact on individuals with Rheumatoid Arthritis (RA). Fatigue Severity Scale (FSS) is the most wi...