As the challenges of cost of acquisition, patient risk, and analysis of MRI in RA are dealt with, the modality will likely play an increasing role as an efficacy endpoint in clinical trials. The superior evaluation of therapeutic signal should gain increasing momentum among sponsors and regulatory...
Learn about RITUXAN® (rituximab) treatment for rheumatoid arthritis (RA) patients including efficacy, safety, MOA and dosing. Please see Important Safety Information including Boxed Warning and Full Prescribing Information for more information.
Learn about RITUXAN® (rituximab) treatment for rheumatoid arthritis (RA) patients including efficacy, safety, MOA and dosing. Please see Important Safety Information including Boxed Warning and Full Prescribing Information for more information.
Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these ...
Rheumatoid arthritisis one of the autoimmune diseases which mainly affects the joints. Inflammation plays a significant role in rheumatoid arthritis. Thus, various classes ofantiinflammatory drugshave been tested inclinical trialsin the treatment of rheumatoid arthritis. Bakhtiari et al.[69]have tested ...
Consistent with findings from clinical trials, in a retrospective cohort study, Janus kinase inhibitors improved pain associated with rheumatoid arthritis as well as or better than biologic DMARDs in clinical practice. Sarah Onuora Research Highlights07 Oct 2024Nature Reviews Rheumatology ...
The treatment of rheumatoid arthritis (RA) has always been a challenge. In the last 5 years, many leaders in the field have emphasised the potential of early and aggressive therapy either with single or multiple slow-acting antirheumatic drugs (SAARDs). Single agents, if given early enough, ...
There is no singular test for diagnosing rheumatoid arthritis. The diagnosis is based on the clinical presentation. What are the diagnostic criteria for rheumatoid arthritis? Presentation of the joints involved Characteristic joint swelling and stiffness in the morning The presence of blood rheumatoid fac...
- 《Arthritis & Rheumatism》 被引量: 596发表: 1995年 Longterm safety of patients receiving rituximab in rheumatoid arthritis clinical trials. Objective.To evaluate the longterm safety of rituximab in clinical trials in patients with rheumatoid arthritis (RA).Methods.Pooled analysis of safety data....
The aims of this study are to describe the characteristics of clinical trials in rheumatoid arthritis (RA) listed in ClinicalTrials.gov and examine existing trends in study design, funding sources, outcomes, and drugs under investigation. We conducted a survey of ongoing clinical trials in RA regi...