Objectives The association between age of rheumatoid arthritis (RA) onset and joint erosions remains unclear. We investigated the effects of age of RA onset on incident joint erosion and the progression of radi
Rheumatoid arthritis, chronic, often progressive disease in which inflammatory changes occur throughout the connective tissues of the body. Chronic inflammation of synovial membranes irreversibly damages joint cartilage. Learn more about the symptoms, pr
Rheumatoidarthritis(RA) is an autoimmune disease that causes chronic inflammation of the joints. Autoimmune diseases are illnesses that develop when the body's immune system attacks its tissues. The immune system contains a complex organization of cells and antibodies designed normally to "seek and de...
The most likely period of onset for women is around menopause. Rheumatoid arthritis is uncommon in men younger than age 45, but its incidence approaches that of women in older men. Before menopause, it is common for women to develop rheumatoid arthritis within a year of pregnancy. Interestingly...
Box 1 Global trends in rheumatoid arthritis Increasing over time Prevalence and incidence Age at disease onset Decreasing over time Mortality (including cardiovascular mortality) Orthopaedic surgeries Time between diagnosis and initiation of anti-rheumatic therapies ...
Imanaka, T, Shichikawa, K, Inoue, K (1997) Increase in age at onset of rheumatoid arthritis in Japan over a 30 year period. Ann Rheum Dis 56: pp. 313-316Imanaka T, Shichikawa K, Inoue K, Shimaoka Y, Takenaka Y, Wakitani S. Increase in age at onset of rheumatoid arthritis in...
The immunopathogenesis of rheumatoid arthritis (RA) spans decades, beginning with the production of autoantibodies against post-translationally modified proteins (checkpoint 1). After years of asymptomatic autoimmunity and progressive immune system remod
Rheumatoid arthritis is an autoimmune disease that causes inflammation of the joints as well as other parts of the body. It commonly affects the wrists, hands and knees.
Borah DJ, Iqbal F (2007) Anemia in recent onset rheumatoid arthritis. JK Sci 9(3):120–122Borah DJ, Iqbal F. Anemia in recent onset Rheumatoid Arthritis. JK Science. 2007;9(3):120-22.Borah DJ, Iqbal F. Anemia in Recent Onset Rheumatoid Arthritis. JK Science, 2007;9(3):120-122....
Rheumatoid arthritis is thought to have a longpreclinical phasethat is marked by the presence of autoantibodies without the symptoms of arthritis.Aho et al. (1991)followed over 7000 Finnish individuals over the age of 30 years for the development of RA. Twenty-one individuals developed RA, 15 ...