A definition of RML was stated in 231 studies (37.6%), including a precise creatine kinase level (CK) cut-off most frequently (67.1%). In 53/231 (22.9%) studies the CK cut-off was >5脳 upper limit of normal (ULN), and in 64/231 (27.7%) studies>1000IU/L. Further components of...
Rhabdomyolysisis characterized bymuscle necrosisand the release of intracellular muscle constituents includingCK,myoglobin, calcium, and potassium. CK levels greater than five times baseline are a sensitive definition ofrhabdomyolysis. Rhabdomyolysis can be due to inherited or acquired causes, and the severi...
Rhabdomyolysis by definition means damage to skeletal muscle. It was initially called “crush syndrome,” as it was identified in 1940 during the London Blitz in patients whose limbs were crushed. These patients survived their initial injury, only to die of renal failure several days later. The ...
In this study in 52,1% of the patients needed KRT, which is considerably more than in other studies [22, 23, 35, 36], but these did not only include critically ill patients with high disease severity and the definition of rhabdomyolysis differed in some cases [22, 23, 35, 36]. Higher...
Taking into account the CK activity cut-off of >1000 IU/L (or more than five times the upper normal limit) and the lack of signs of AKI or myoglobinuria, the definition of ‘mild RM’ was fulfilled [6]. Regarding the diagnosis of RM, serum CK activity is the most sensitive marker ...
markers predictive of rhabdomyolysis-related renal complications have been poorly investigated despite the importance of being able to identify patients at risk to whom administering appropriate fluid rehydration with the goal of urine output of 300 mL/h is recommended [2]. Serum CK level is routinely...