Carbon nanotubes (CNT) have unique properties that make them an excellent option for use as drug carriers. However, to make them safe for the human body, their walls are typically coated with a layer of peptide, which also helps to neutralize their toxic
tinctorius hyphae aggregated to form the mantle. Other functions mediated by RGD RGD peptides have found utility in the inhibition of other cell–cell interactions as well. For example, contact-dependent inhibition of the growth of C. albicans hyphae by IL2-activated large granular lymphocytes can...
Download: Download full-size image Fig. 2. Serum protein stability study of fluorescent peptides at various time intervals shows F-HM possess less bio-stability (<65 % up to 24 h) as compare to both of its cyclic analogues F-HMC-1 (≥97 % up to 24 h) and F-HMC-2 (≥93 %...
we have prepared poly(lactic acid-co-glycolic acid) (PLGA) nanoparticles with a PEGylated surface decorated with two different arginine-glycine-aspartic acid (RGD) peptides: one is cyclic
Following this approach, RGD-containing peptides have been successfully conjugated with diverse anticancer drugs, as doxorubicin, doxsaliform, monomethylauristatin E, cisplatin, camptothecin and paclitaxel15,16. An important issue is also the increase in water solubility of the drug due to peptide or...
Carrier peptides can deliver other components of cosmetic preparations when these are applied topically. In this study, we explored the possibility of synthesis of a phytochemical (gallic acid) and a peptide for use as a cosmetic ingredient. We assessed 3 aspects of the novel compound (galloyl-...
Novel amphiphilic conjugates consisting of an Arg-Gly-Asp (RGD) peptide binding motif and aliphatic fatty acids of varying chain length (C10-C18) were synthesized and evaluated for their ability to form micelles and bind specifically to alphaVbeta3 integrin over-expressing tumor cells. The aphil...
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The binding of integrin proteins to peptide sequences such as arginine-glycine-aspartic acid (RGD) is a crucial step in the adhesion process of mammalian cells. While these bonds can be examined between purified proteins and their ligands, live-cell assays are better suited to gain biologically ...
VitroGel® RGD is a tunable, xeno-free hydrogel system modified with cell adhesive peptide RGD to promote cell attachment and cell-matrix interactions during 3D cell culture.