Rexulti carries aBoxed Warningfor an increased risk of death in elderly patients with dementia-related psychosis. Increased risk of death in elderly people with dementia-related psychosis. Medicines like Rexulti can raise the risk of death in elderly people who have lost touch with reality (psychosi...
(5.4) WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS • Tardive Dyskinesia: Discontinue if clinically appropriate. (5.5) WITH DEMENTIA-RELATED PSYCHOSIS and SUICIDAL THOUGHTS AND BEHAVIORS • Metabolic Changes: Monitor for hyperglycemia/diabetes mellitus, See full prescribing information for complete ...
See full prescribing information for REXULTI. REXULTI® (brexpiprazole) tablets, for oral use Initial U.S. Approval: 2015 WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS and SUICIDAL THOUGHTS AND BEHAVIORS See full prescribing information for complete boxed warning. ...
Patent use: TREATMENT OF SCHIZOPHRENIA IN ADULTS AND PEDIATRIC PATIENTS AGES 13 YEARS AND OLDER ✓ Drug product April 12, 2026 ✓ Patent use: TREATMENT OF SCHIZOPHRENIA ✓ Drug product Piperazine-substituted benzothiophenes for treatment of mental disordersPatent 9839637*PEDIssued: December 12...
Increased Mortality in Elderly Patients with Dementia-Related Psychosis; and Suicidal Thoughts and Behaviors Elderly patients with dementia-related psychosis treated with antipsychoticdrugsare at an increased risk of death. Rexulti is not approved for the treatment of patients with dementia-related psychosis...
“Agitation associated with dementia due to Alzheimer’s disease can be very challenging and emotionally distressing for patients and family members caring for them. With the publication of the complete Study 213 data, the evidence of...
For this treatment, researchers conducted two six-week clinical trials. The trials included more than 1,000 patients whose symptoms were not adequately treated by taking an antidepressant alone. Those who took Rexulti and an antidepressant had fewer symptoms of depression than those who took a ...
WARNING: INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at increased risk of death. REXULTI is not approved for t...
REXULTI is not approved for the treatment of patients with dementia-related psychosis. Neuroleptic Malignant Syndrome (NMS): NMS is a potentially fatal symptom complex reported in association with administration of antipsychotic drugs including REXULTI. Clinical signs of NMS are hyperpyrexia...
Rexulti (generic name: brexpiprazole) is an atypical antipsychotic used to treat patients with major depressive disorder (MDD), schizophrenia, and agitation associated with dementia due to Alzheimer’s disease. In Rexulti studies, some people started to see results 1 or 2 weeks after starting treatm...