Schizophrenia (adults)1 mg daily2 to 4 mg daily4 mg daily Schizophrenia (age 13-17 years)0.5 mg daily2 to 4 mg daily4 mg daily Agitation associated with dementia0.5 mg daily2 mg daily3 mg daily Detailed Rexulti dosage information
PO (Adults): 0.5 or 1 mg once daily initially; may be ↑ to 2 mg once daily (not to exceed 3 mg once daily); Known CYP2D6 poor metabolizers: use 50% of the usual dose. Concurrent use of strong CYP2D6 inhibitors (schizophrenia only) or CYP3A4 inhibitors: use 50% of the usual...
The recommended starting Rexulti dosage for the adjunctive treatment of MDD in adults is 0.5 mg or 1 mg once daily. Titrate to 1 mg once daily, then titrate to the target dosage of 2 mg once daily (based on the patient’s clinical response and tolerability, increase the dosage at weekly ...
2.2 Treatment of Schizophrenia The recommended starting dosage for REXULTI is 1 mg once daily on Days 1 to 4, taken orally with or without food [see Clinical Pharmacology (12.3)]. The recommended target REXULTI dosage is 2 mg to 4 mg once daily. Titrate to 2?mg once daily on Day 5 ...
https://www.thedailybeast.com/alzheimers-brain-damage-could-be-repaired-with-experimental-bms-984923-oral-drug 现在还为时过早,但一项新的老鼠试验结果肯定令人鼓舞。美国有近 600 万成年人患有阿尔茨海默病。这种疾病通常在 60 岁之前发作,并且无法治愈,尽管有一些药物可以缓解记忆症状和其他认知变化。 然而,...
1 mg/day 2 to 4 mg/day 4 mg/day Schizophrenia Pediatric (13 - 17 years) (2.2) 0.5 mg/day 2 to 4 mg/day 4 mg/day • Moderate to Severe Hepatic Impairment (Child-Pugh score ≥7): Maximum recommended dosage is 2 mg once daily for patients with MDD and 3 mg once daily for pa...
美国FDA 依匹哌唑(Rexulti,brexpiprazole)FDA官方说明书 英文原版.pdf,HIGHLIGHTS OF PRESCRIBING INFORMATION WARNINGS AND PRECAUTIONS These highlights do not include all the information needed to use • Cerebrovascular Adverse Reactions in Elderly Patients
In Study 213, the agitation symptoms of the group randomized to receive either a 2 or 3 milligram daily dose of brexpiprazole significantly improved after 12 weeks of treatment, compared to the placebo group, when measured using...