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Humans and animals are not always rational. They not only rationally exploit rewards but also explore an environment owing to their curiosity. However, the mechanism of such curiosity-driven irrational behavior is largely unknown. Here, we developed a de
We further queried (1) perceived loneliness (self-report of a five-point Likert-like scale) and (2) the number of prior attempts at harming oneself in the past year. These variables (henceforth ‘survey variables’), along with the judgment variables (described below), were inputs for ...
CRCHUM and Montreal Diabetes Research Center, Montréal, QC, Canada Cecile Hryhorczuk, Léa Décarie-Spain, Thierry Alquier & Stephanie Fulton Department of Physiology, Université de Montréal, Montréal, QC, Canada Cecile Hryhorczuk Department of Pharmacology, Rutgers New Jersey Medical School, Physi...
The orbitofrontal cortex (OFC) encodes value and plays a key role in value-based decision-making. However, the attentional modulation of the OFC’s value encoding is poorly understood. We trained two monkeys to detect a luminance change at a cued locatio
Kittel, University of Würzburg) under the same conditions as the experiments with UAS-ChR2-XXL, as well as using UAS-Chrimson as the effector101 (Bloomington Stock Center no. 55134). For the UAS-Chrimson experiments, 630 nm red light at an intensity of 3.5 µW/mm2 was used, ...
Lumbar puncture (LP) was performed at the Emory General Clinical Research Center between 1100 and 1500 h by an attending anesthesiologist 1 day after blood sampling, as described previously [31, 69]. Approximately 10 mL of CSF was collected for each subject after discarding the initial 1...