Our data show that inflammasome function, through the NLRP3–ASC–caspase 1–GSDMD axis, in bone marrow stromal cells controls the rate of hematopoietic stem cell proliferation and thereby reduces premalignant to malignant transformation. Research Briefing02 Jan 2025 Past interactions of T cells with...
By comparing protein engineering and DNA nanotechnology, we highlight molecular architectures that are relevant in biotechnology, biomedicine and synthetic biology research, and identify emerging areas for research such as hybrid materials composed of protein and DNA/RNA....
A nucleotide that performs a nucleophilic attack on the 5′ splice site in the first step of splicing. Exitrons Non-constitutive introns located within annotated protein-coding exons. Exon junction complex (EJC) A protein complex assembled on the spliced mRNA at the junction of two exons. Falsi...
et al. Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein β isoform and up-regulation of the eukaryotic translation initiation factor 2α are correlated with neoplastic transformation of mammary epithelial cells.Cancer Res.56, 4382–4386 (1996). CASGoogle Scholar...
is questioned by life extensionists. The phrase most often quoted is that "believing cryonics could reanimate somebody who has been frozen is like believing you can turn a hamburger back into a cow." Some cryonics enthusiasts believe that this transformation will be "no problem" for ...
(MolecularBiotechnologyLaboratoryforTriticeaeCrops).TheplasmidasawholeorCleanCassetecanbeusedingeneguntransformationofwheat.Areviewismadeonrecentdevelopmentsinproteinexpressiontechnologiesinplants,keepinginviewtheimportanceofbiopharmingasanemergingfield.Theinfectiousdiseasesalongwithcancersaretheworldleadingcausesofdeathsin...
BBA Reviews on Cancercovers the whole field of thebiologyandbiochemistryofcancer, emphasizing oncogenes and tumor suppressor genes, growth-related cell cycle control signalling, carcinogenesis mechanisms, cell transformation, immunologic control mechanisms, genetics of human (mammalian) … ...
My only constructive feedback is that I wish the app will let you calculate “net carbs” I.e total carbohydrates minus dietary fibre and let’s u see this in the macro pie chart as I’m on a Ketogenic diet. But this app has been so helpful in my fitness transformation. Good job!
SAP kinase transformationThe oncogenic Bcr-Abl variant of the c-Abl tyrosine kinase transforms cells by a mechanism dependent on activation of the stress-activated protein kinase (SAPK). Other work has shown that c-Abl interac...
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