et al. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes 61, 364–371 (2012). Article PubMed PubMed Central CAS Google Scholar Samuel, B. S. et al. Effects of the gut microbiota on host adiposity are modulated by the...
For mass spectrometry (MS) analysis, the proteins of interest are proteolytically digested — the resulting peptides are easier to handle, easier to sequence and have better detection efficiencies than intact proteins. Thousands of peptides can be introduced to the mass spectrometer through 'on-line...
The regulation of SREBP-1 is at the core of numerous metabolic diseases, such as obesity, diabetes, atherosclerosis, non-alcoholic fatty liver disease, hepatosteatosis, neurodegenerative diseases, and cancer [40,41,42,43,44]. The latter relies on membrane biogenesis and energy production for cell ...
Moreover, through surface modification, nanoparticles have been coupled with various targeting ligands, including peptides, antibodies, and aptamers, allowing for the direct delivery of the load to the designated tumor with an increased efficacy and decreased toxicity [24,25,26,27]. Research on ...
Spirin, A. S. & Finkelstein, A. V. inMolecular Machines in Biology:Workshop of the Cell(ed. Frank J.) 158–190 (Cambridge Univ. Press, 2012).This book chapter describes the operation of a ribosome, relating its directional motion and sequence-specific peptide synthesis to a Brownian ratc...
s Baby Lips) but it’s thicker than a traditional chapstick. The stick is thicker primarily because it has what Almay calls an “anti-aging” pink center core which contains primarily emollients (glycerin, fatty acids, waxes, etc.) and small amounts of antioxidants and peptides. The lovely...
effective, but you'll have to pay for that quality. A simple combination of a core supplement and one of its boosters will set you back at just under $100/month. It's not a great deal compared to minoxidil, which you can get elsewhere without a prescription for a fifth of that cost...
《Nature reviews Drug discovery》共发表704篇文献,掌桥科研收录2004年以来所有《Nature reviews Drug discovery》期刊内所有文献, 期刊刊频为Monthly,ISSN为1471-1776,
Title discontinued as of 2002; Articles EditorialNo access Dendrimers Stephan Diekmann, Thisbe K Lindhorst May 2002 Research articleAbstract only Core and periphery functionalized dendrimers for transition metal catalysis; a covalent and a non-covalent approach ...
Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally occurring peptides that can combat infections through their direct microbicidal properties and/or by influencing the host’s immune responses. The unique ability of CHDP to control infections as well as resolve...