(1)sustained AR activation by enhancing intracellular conversion of adrenal androgens to dehydrotestosterone via a de novo route;(2)AR hypersensitivity;(3)promiscuous activation of AR signaling;and(4)outlaw pathways.Recent advances in the treatment of CRPC include novel medicinestargeting AR signaling ...
biologics and veterinary medicines industries. Unlike other media,FDA Revieweliminates time-wasting minutia and presents in clear, concise language the essence of what's really important - and why. It is the publication that FDA officials themselves read. Delivered in the middle of each week,FDA ...
evaluated the effect of diabetes medications, namely biguanides, incretin-based medicines, alpha-glucosidase inhibitors (AGIs), insulin secretagogues, thiazolidinediones, and insulins, on the risk of developing any of study cancers, specifically breast, lung, colorectal, prostate, liver, or pancreatic...
The dMMR-/MSI-/high TMB- group includes both common and rare cancers (e.g., prostate, breast and bile duct/gall bladder cancers, sarcoma, brain tumour and endocrine tumour). These different categories likely reflect different contributions of carcinogenic mechanisms, which differ between cancer ...
Cancer is one of the biggest causes of morbidity and mortality in the world, making it an important target for natural medicines with less toxicity [60]. Zhujieshen is well-known for its potential anti-cancer effects. Studies have shown that chikusetsusaponins IVa can also inhibit prostate can...
org/publications/journals/value-in-health/abstract/Volume-19--Issue-3/Cost-Effectiveness-Analysis-of-Abiraterone-in-Patients-with-Metastatic--Castration-Resistant--Prostate-Cancer-with-Progression-after-Receiving-Chemotherapy-with-Docetaxel--Compared-with-Receiving-only-Palliative-Support--The-Perspective-of....
medicines to prevent or reduce the effects of liver cancer. Recent studies have shown growing interest in herbal products, nutraceuticals, and Chinese medicines as potential treatments for liver cancer. These substances contain unique bioactive compounds with anticancer properties. The causes of liver ...
Should we advise parents to administer over the counter cough medicines for acute cough? Systematic review of randomised controlled trials AIMS: To determine the effectiveness of over the counter () cough medicines for acute cough in children.: Systematic review of randomised controlled trials... ...
Rhubarb, the rhizome and root of Rheum palmatum L. from the Polygonaceae family, is a globally important medicinal plant, especially in eastern Asia. It ha
3D printing of tablets containing multiple drugs with defined release profiles. Int J Pharm. 2015;494:643–50. Article CAS PubMed Google Scholar Goyanes A, Wang J, Buanz A, Martínez-Pacheco R, Telford R, Gaisford S, et al. 3D printing of medicines: engineering novel oral devices with...