In conclusion, retinal degeneration, most pronounced of pRNFL and GCIPL, occurs in all subtypes. Using the current state of technology, longitudinal assessments of retinal thickness may not be suitable on a sin
Retinitis pigmentosa is a genetic disease causing degeneration of retinal pigment epithelial and photoreceptor cells. Here, the authors show that PNPLA6 regulates choline metabolism for retinal homeostasis, and its dysfunction leads to degeneration, which can be rescued by choline supplementation. ...
2 Retinal degeneration There are many types of retinal degenerative diseases that affect the human eye. These conditions vary in their etiology and inheritance patterns, but at the end visual loss is the common consequence in many of them. Retinal degenerations are common disease that affects an ...
Age-related, diabetic and genetic retinal degeneration accounts for more than half of patients with blindness in developed countries, and the incidence of retinal disease in China continues to rise due to the increasing population of elderly people, and a growing number of people with diabetes and/...
What is Macular degenerative disease? What is Plus disease in retinopathy of prematurity? What is myopic macular degeneration? What is juvenile macular degeneration? What forms of macular degeneration are treatable? What is the etiology of cataracts? What causes Macular degenerative disease? What do ...
The retinal pigment epithelium in health and disease Curr. Mol. Med., 10 (9) (2010), pp. 802-823 Google Scholar [10] M.R. Kozlowski RPE cell senescence: a key contributor to age-related macular degeneration Med. Hypotheses, 78 (4) (2012), pp. 505-510 View PDFView articleView in ...
RETINAL degenerationGENE therapyCORNEAL dystrophiesPurpose To provide an overview of the recent developments in genetics of inherited retinal dystrophies and dysfunctions.Methods A systematic approach, supported by case presentations, will be used to illustrate an overview of new insights into genotypes ...
特征:degeneration of photoreceptor OCT上 disruption of photoreceptor inner segment ellipsoid zone 与 visual loss相关 retinal thickness ↓, esp. in outer retinal layers RPE的变化特征是:focal areas of mobilization of pigment (hypo / hyper-pigmentation) ...
AMD and Retinal Disease : Retinal disease can have devastating consequences. Age-related macular degeneration (AMD) is the leading cause of legal blindness among adults in the US. Early diagnosis and treatment can help prevent or delay disease progressio
Huang et al. explore using aqueous humor to identify biomarkers associated with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) through an affinity-based proteomics approach. They find 82 significantly altered proteins in GA, such as SMOC2 and IL-6. ...