Verrucous carcinomas are a rare variant of squamous cell carcinoma. Vulval verrucous carcinoma comprises only 1% of vulval malignancies. This case report discusses the successful management of aggressive recurrent vulval verrucous carcinoma with acitretin, an oral synthetic retinoid used to manage ...
There are other reports in New Zealand White rabbits administered doses of greater than 0.2 mg/kg/day (3.3 times the maximum human systemic dose adjusted for total body surface area) of an increased incidence of domed head and hydrocephaly, typical of retinoid-induced fetal malformations in thi...
Common Brand Name(s):Altreno, Atralin, Refissa, Renova, Retin-A, Retin-A Micro Common Generic Name(s):tretinoin Pronunciation:TRET-i-noyn Drug Classes:anti-acne agent, anti-wrinkle agent, retinoid Availability:prescription only, generic available for some forms ...
Objective To investigate the alteration of retinoid X receptor α(RXRα) mRNA level in normal human keratinocytes after acitretin and/or NB-UVB irradiation treatment. Methods After a 12-hour incubation with 10-7-10-6 mol/L acitretin and/or following 50-100 mJ/cm2 NB-UVB irradiation in ...
Synthetic retinoid fenretinide in breast cancer chemoprevention. Expert Rev Anticancer Ther. 2007;7(4):423–32. Article CAS PubMed Google Scholar Sheikh MS, Shao ZM, Li XS, Ordonez JV, Conley BA, Wu S, et al. N-(4-hydroxyphenyl)retinamide (4-HPR)-mediated biological actions involve ...
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. 体外活性 Acitretin 通过激活ADAM10启动子活性(EC(50)为1.5 mM),提升成熟ADAM10蛋白水平,导致神经母细胞瘤细胞中α-与β-分泌酶活性比例增加二至三倍。[1] Acitretin (5-20 μM)降...
产品编号 T1872 别名芬维A胺, MK-4016, 4-hydroxy(phenyl)retinamide, 4-HPRCas号 65646-68-6 Fenretinide (4-HPR) 是一种可口服的合成类维生素 A 衍生物,具有潜在的抗肿瘤和化学预防活性。 规格价格库存数量 5 mg ¥ 229 现货 10 mg ¥ 373 现货 50 mg ¥ 648 现货 100 mg ¥ 995 现...
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This new retinoid combination (Retinsphere technology) were effective and safe as maintenance therapy after post-treatment response to oral isotretinoin in patients with acne. Resumen Introducción Existe un alto porcentaje de pacientes que presentan reidivas de acné tras el uso de isotretinoína oral...
Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease[1][2][3]. 体内研究 (In Vivo) Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the ...