This can lead to improved disease management, response, survival and use of financial resources.HayonDvilanskyShpilbergHayon T, Dvilansky A, Shpilberg O, et al. Appraisal of the MTT-based assay as a useful tool for predicting drug chemosensitivity in leukemia[J]. Leuk Lymphoma, 2003, ...
A modified wound scratch assay was used to assess the effects of metformin on the ability of CRC cells to migrate. Metformin was added at scalar concentrations ranging from 5 to 0.3 mM, derived from the MTT assays and including non-cytostatic doses of the drug (Supplementary Fig.S2). I...
However, IC 50 values by the MTT assay were higher in 90% of the drugs than those found by the ATP assay. In addition to this, there was a statistically significant difference between the dose response curves of the assays, which was dependent on the drugs of choice. We recommend caution...
The affinity of reactive nitrogen species toward the guanine base of DNA was evaluated by density functional theory calculations. Expression and localization of nuclear factor NF-kB was determined using imaging cytometry, while cell viability assay was evaluated by MTT assay. Herein, we presented that...
Quantitation of apoptotic bodies was carried out by immunoassay and corrected to cell number as determined by MTT assay. In each cell line, addition of hCGβ reduced the number of apoptotic bodies dose-dependently, indicating a diminished apoptotic rate. Furthermore, TGFβ1-induced apoptosis could...
The toxicity of NAC on the cells was studied by the LDH cytotoxicity assay; cell proliferation was examined by the MTT method. MPST activity and sulfane sulfur level were also analyzed in the NAC-treated cells. Results: The addition of NAC to the medium, in non-cytotoxic concentrations, ...
Current extraction methods for macroalgal-derived metabolites are, however, problematic due to the complexity of the algal cell wall which hinders extraction efficiencies. The use of advanced extraction methods, such as enzyme-assisted extraction (EAE), which involve the application of commercial algal ...