PATIENT complianceRESPIRATORY obstructionsRestrictive lung disease (predominantly in patients with neuromuscular disease (NMD) and ribcage deformity) may induce chronic hypercapnic respiratory failure, which represents an absolute indication to start home NIV (HNIV). However, in the early phases of NMD,...
Total lung capacity (TLC) measured via plethysmography or nitrogen wash out. It is considered the gold standard for characterizing restrictive thoracic disease. In 2005, the ATS guidelines recommended that the forced expiratory volume in one second (FEV1) be used to grade restrictive deficits on ...
Seven patients died of pulmonary or systemic infection, and one patient died due to relapse of the primary disease. Conclusion Severe restrictive lung defect could develop in selected cases in the late-phase after HSCT and could be a unique clinical entity with specific radiographical findings....
Although most cases of restrictive cardiomyopathy are idiopathic, it is important to fully evaluate the patient for possible systemic disease that can cause restrictive myocardial disease. Constrictive pericarditis should be considered in the differential and can cause similar signs and symptoms. The differ...
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structure and function. The V429L variant is a strong candidate for a disease-causing mutation that may be associated with the patient’s reported intracranial haemorrhage, anaemia, and thrombocytopenia. However, the novel homozygous nonsense variant (c.80 G > A) in exon 1/16 of theDC...
One of these patients was listed for heart-lung transplantation, but died while waiting. A single patient (PVRI = 14.0; 10.4 with nipride) was offered cardiac transplantation as a high-risk candidate; however, the patient’s family refused listing. Evaluation via unpaired Student’s t-tests ...
Inherited cardiomyopathies as a collective group, are relatively common cardiac disorders. Individuals can present with symptoms of chest pain, dyspnoea, palpitations, syncope and with progressive heart failure or sudden cardiac death. Genetic mutations
Washington D. C. 20307-0001 ABSTRACT Walter Reed Army Institute of Research and Oak Ridge National Laboratory have developed a prototype pulmonary diagnostic system capable of extracting signatures from adventitious lung sounds that characterize obstructive and/or restrictive flow. Examples of disorders tha...
IMPLICATIONS: Spirometry must be used with caution when grading the severity of restrictive pulmonary disease.DISCLOSURE: The following authors have nothing to disclose: Sean Roark, Aaron Holley, Timothy QuastNo Product/Research Disclosure InformationWalter Reed National Military Medical Center, North ...