While autophagy is responsible for follicular atresia at the moment of birth, apoptosis is the dominant form of postnatal ovarian atresia [17]. Interestingly, Danilovich et al. [22] postulated that GH and IGF-1 prevent the apoptosis of granulosa cells. The aim of this study was to examine ...
Beatrice Yue (University of Illinois at Chicago). Mice Mice used in this study were generated in the study35. In summary Optnflox/flox mice on a C57BL/6 background were generated using a targeting vector-inserted LoxP site that flanks the first coding exon and a neomycin selection cassette....
Genome scans based on outlier analyses have revolutionized detection of genes involved in adaptive processes, but reports of some forms of selection, such as balancing selection, are still limited. It is unclear whether high throughput genotyping approaches for identification of single nucleotide polymorph...
Restriction-modification systems are a diverse class of enzymes. They are classified into four major types: I, II, III and IV. We have previously proposed the existence of a Thermus sp. enzyme family, which belongs to type II restriction endonucleases (R
Aerobic respiration is required for optimal efficiency of metabolism in mammalian cells. Under circumstances when oxygen utilization is impaired, cells survive by anerobic metabolism. The malignant cell has cultivated the use of anerobic metabolism in an