To analyze the impact of pro-migratory stimuli (e.g. growth factors) on the migratory behavior of epithelial cancers and to generate a corresponding mathematical model we focused on cell lines derived from human non-small cell lung cancer (NSCLC, subtype adenocarcinoma) since tumor cell disseminati...
we examined the sensitivity of GSCs with high levels of MKP1 to chemotherapy. We measured the proliferative capacity of GNS166 cells in the presence of TMZ finding that cells with elevatedMKP1showed significant drug sensitivity and impaired cell growth when compared to control cells (Fig.6d). In...
Corn (Zea mays) responses to competition: Growth alteration vs. limiting factor. Agron. J. 101:1522-1529. doi:10.2134/ agronj2008.0213xClay, S. A., D. E. Clay, D. P. Horvath, J. Pullis, C. G. Carlson, S. Hansen, and G. Reicks. 2009 . Corn response to competition: growth ...
Transforming growth factor (TGF)-β, a pleiotropic cytokine released by both immune and non-immune cells in the gut, exerts an important tolerogenic action by promoting regulatory T cell differentiation. TGF-β also enhances enterocyte migration and regulates extracellular matrix turnover, thereby playi...
Refers to Comment on ‘Insulin-like Growth Factor 1 – A Novel Biomarker of Abdominal Aortic Aneurysm’ European Journal of Vascular and Endovascular Surgery, Volume 43, Issue 3, March 2012, Pages 360 D. Koole, J.A. van Herwaarden, G. Pasterkamp, F.L. MollView PDFPrevious...
The International Monetary Fund (IMF) noted that China will achieve stable economic growth in 2023 and become the largest positive factor of the world economy. Multiple international investment banks and financial institutions including Morgan Stanley, Goldman Sachs, HSBC, Barclays and Natixis have revis...
The lack of an effect at a higher Cd dose (10 μmol/L) suggests the effect of high Cd doses on the activity of other transcriptional factors, as the AhR is not the only factor regulating CYP expression[69, 70]. ROS are often related to Cd toxicity[71]. Increases in lung leukocyte ...
A WATER shortage at any stage of plant growth usually results in a reduction in vegetative growth, but many annual crop plants are especially sensitive to changes in soil moisture conditions during the period from flower initiation to the development of full flower 1–3 . It has been shown tha...
Epidermal growth factor receptor (EGFR) signalings have recently been implicated in the genesis and progression of cholangiocarcinomas. Thus, the EGFR kinase inhibitor appears to be promising in the treatment of this cancer. The response-predicting mutations in the tyrosine kinase domain of EGFR gene...
Our research used adeno-associated virus (AAV) to carry the target gene to transfect neural stem cells. Transfected NSCs can express nerve growth factor (NGF) navigated by five hypoxia-responsive elements (5HRE). Therefore, the 5HRE-NGF-NSCs could express NGF specifically in hypoxia sites to ...