ZICHA J, KUNES J, DAVID-DUFILHO M, PERNOLLET MG, DEVYNCK MA: Cell calcium handling and intracellular pH regulation in hereditary hypertriglyceridemic rats: reduced platelet response to thrombin stimulation. Life Sci 59: 803-813, 1996a.
Cytosolic Ca2+ Measurement The cytoplasmic Ca2+ concentration ([Ca2+]i) in ECs was measured using the Ca2+-sensitive fluorescent dye Fura-2/AM (10, 21). Cells were grown to confluence on gelatin-coated glass coverslips and then washed two times and incubated for 12 h at 37 °C in medium...
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The down- regulation of these genes may be a strategy to save energy and resources assuming that the population is already acclimated to elevated temperature. Down-regulation of genes associated with oxidative stress and cell apoptosis in the Cagayan population may be attributed to the thermotolerance...
Difference in platelet cytosolic calcium response to thrombin in alcoholic withdrawal and sober patient. Tan CH,Lee HS,Kua EH,et al. Journal of Studies on Alcohol . 1995Tan CH, Lee HS, Kua EH, Yeo B, Ang A. Difference in platelet cytosolic calcium response to thrombin in alcoholic ...
It has been proposed that Nalp3 may also respond to cytosolic lipids such as arachidonic acid and lysophospholipids generated by iPLA2 (10). Phospholipase-generated signals in ATP-treated macrophages may also synergize with elevated cytosolic Ca2+ in stimulating ROS production, as Ca2+ levels or ...
Some studies have shown that IP3Rs and RyRs are related to oxidative stress [11]. Therefore, oxidative stress is a key regulator of Ca2+ levels in acinar cells. Altogether, these changes induce cell necrosis and inflammatory cascade. 2.2. Acinar cell organelles disorders Recent studies have ...
Furthermore, increased mortality in critically ill patients has also been related to elevated ADMA levels [226,227]. The correlation between arginine and ADMA, defined as the L-arginine/ADMA ratio, is decreased in adult sepsis patients [228] indicating a role of ADMA in the modulation of ...
We demonstrate that by binding to receptors which were distinct from the formylated peptide receptor, n-SP (100 nM-400 μM) directly triggered the NADPH-oxidase response, elevated cytosolic free Ca2+, and caused the polymerisation of G-actin. However at lower concentrations (1–100 nM), in ...