作者: Campbell Craig, Selby Kathy, McMillan Hugh, Vajsar Jiri, Korngut Lawrence, Brais Bernard, MacKenzie Alex, Oskoui Maryam 展开 摘要: As Canadian neuromuscular specialists caring for children and adults with spinal muscular atrophy (SMA), we write to express our disappointment with the recent...
The objective of the paper is to examine how firms have dealt with the trade-off between flexibility and uncertainty that is characteristic for the decision-making of firms in coping with self-regulatory initiatives in general and the comply-or-explain principle in corporate governance in particular...
and R01CA237263 and R01CA248526 to A.V.; the US Department of Defense (DOD) Breast Cancer Research Program (BRCP) Expansion Award BC191374 to A.V.; the Alvin J. Siteman Cancer Center Siteman Investment Program (supported by The Foundation for Barnes-Jewish Hospital, Cancer Frontier Fund...
Campino S, Kwiatkowski D, Dessein A (2006) Mendelian and complex genetics of susceptibility and resistance to parasitic infections. Semin Immunol 18:411–422 PubMed CAS Google Scholar Carey LA, Perou CM, Livasy CA, Dressler LG, Cowan D, Conway K, Karaca G, Troester MA, Tse CK, Edmisto...
people with advanced HIV disease are more vulnerable to poor COVID-19 outcomes. COVID-19 vaccines are effective and well tolerated in the majority of PWH, though reduced vaccine efficacy, breakthrough infections and faster waning of vaccine effectiveness have been demonstrated in PWH. This is like...
[7,8,9,10,11,12]. While the mechanism behind this sexual dimorphism remains uncertain, one explanation is that sex steroids affect the immune response to sepsis [7,8,10,13]. Age is another major influential factor in the outcome of sepsis since the incidence of sepsis and the associated ...
Twenty-seven volunteers (46.5%) were identified as CC genotype and 31 (53.5%) as CA+AA genotype. Time-group interaction showed that there was no difference in these between two allele groups. However, differences in distribution of respondents or nonresponders according to allele A were ...
Shien K, Papadimitrakopoulou VA, Wistuba II. Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer. Lung Cancer. 2016;99:79–87. Article Google Scholar Snyder A, Makarov V, Merghoub T, Yuan J, Zaretsky JM, Desrichard A, et al....
The ordinal response format typically consists of three to ten response values (e.g., 5-point Likert scale). In the continuous response format, an infinite number (or very large number) of score points can be produced. Description Researchers developing a quality of life measure need to ...
Immunotherapies have emerged as one of the most promising approaches to treat patients with cancer. Recently, there have been many clinical successes using checkpoint receptor blockade, including T cell inhibitory receptors such as cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell...