Conclusions RSV infection is associated with the need for extended hospital stay, ICU care and mortality in adults of all ages with chronic underlying conditions. Presenting signs and symptoms are nonspecific, co-infections occur, and patients often receive antibiotics and anti-influenza therapy. There...
The wide range of estimates offers little useful guidance for decision-making to decrease respiratory infection burden. Large, well-designed epidemiologic studies are therefore still necessary to credibly quantify the burden of respiratory infections among older adults in LTCFs, which will ultimately help...
The(RSV) is one of the most important viral pathogens, causing epidemics of acute respiratory infection (ARI), especially bronchiolitis and pneumonia, in children worldwide. To investigate the RSV burden in Laos, we conducted a one-year study in children <5 years old admitted to Mahosot Hospit...
Objectives High rates of respiratory symptoms and chronic bronchitis (CB) are reported in people with HIV infection (PWH). We investigated the prevalence of respiratory symptoms and CB in PWH and HIV-negative people in the Pharmacokinetic and clinical Observations in PeoPle over fiftY (POPPY) study...
The transcription of viral DNA depends in part on host cell machinery. The replicative cycle in the host cells may be lytic or may result in the establishment of a latent infection, primarily in lymphoid tissue. The symptoms of adenovirus disease are due to the lysis of infected epithelial ...
To these major symptoms of lung disease—coughing, dyspnea, and chest pain—may be added several others. Awheezinessin the chest may be heard. This is caused by narrowing of the airways, such as occurs inasthma. Some diseases of the lung are associated with the swelling of the fingertips...
Symptoms generally appear within four to six days of infection and include runny nose, cough, sore throat, headache, fever, and wheezing. In instances of severe illness, affected individuals may have a high fever, severe wheezing, rapid or laboured breathing, and bluish lips or fingers. ...
; HPIV, human parainfluenza virus; HRV, human rhinovirus; PCF, pharyngoconjunctival fever; HRSV, respiratory syncytial virus; RT-PCR, reverse transcription-polymerase chain reaction; SARS, severe acute respiratory syndrome; SARS-CoV, coronavirus associated with SARS; URI, upper respiratory infection....
We identified seasonal human coronaviruses, influenza viruses and rhinoviruses in exhaled breath and coughs of children and adults with acute respiratory illness. Surgical face masks significantly reduced detection of influenza virus RNA in respiratory d
Moreover, sex differences have been observed in relation to LRTIs, with males, particularly those aged 70 years and above, having a higher incidence [4, 5] and increased immediate mortality following infection [5]. The increased susceptibility of older adults to LRTIs can be attributed to ...