Stewart, C. E.: An epidemiologic study of altered clinical reactivity to respiratory syncytial (RS) virus infection in children previously vaccinated with an inactivated RS vaccine. Amer. J. Epid.89, 405–421 (1969).
The ResPECT study will need 157 independent clus- ters with a median size of 16 participants each to achieve 80 % power to detect a relative risk of 0.75 between N95 and surgical masks at preventing laboratory-confirmed influenza infection, with a Type-I error rate of 0.05. The total number...
This study has some major limitations. Firstly, it was a retrospective study. The assignment was largely based on the choice made by a given patient’s family after the benefits and risks were clearly explained by an interventionalist and surgeon, respectively. Although baseline demographic data an...
Exclusion criteria for both T and LP were the following: (i) bronchopulmonary dysplasia (BPD); (ii) malformation of upper respiratory tract; (iii) immunological and/or metabolic and/or neurological diseases; (iv) any reported respiratory tract infection within 4 weeks prior to enrolment; (v) ...
Ribavirin in respiratory syncytial virus infection A double blind placebo controlled trial is needed, Arch Dis Child, 63 (1988), pp. 986-990 CrossrefGoogle Scholar 286. ER Wald, B Dashefsky, M Green In re ribavirin: A case of premature adjudication? J Pediatr, 112 (1988), pp. 154-158...
The primary safety objective of the Procalcitonin and Lung UltraSonography based antibiotherapy in patients with Lower rESpiratory tract infection in Swiss Emergency Departments (PLUS-IS-LESS) study is to demonstrate a non-inferiority of the PLUS algorithm, in terms of clinical failure by day 28 when...
The human upper respiratory tract (URT) microbiome, like the gut microbiome, varies across individuals and between health and disease states. However, study-to-study heterogeneity in reported case–control results has made the identification of consisten
Lung infection is a major contributor of airway inflammation in CF patients and in turn worsens disease severity. An innovative in vitro study demonstrated the protective effect of 25(OH)D againstPseudomonas aeruginosainfection when vitamin D is administered in the form of liposomes using nebulisation...
pneumonia isolates were collected from children <5 years old with the diag- nosis of acute upper respiratory infection in Beijing, Shanghai, Guangzhou, Shenzhen, Chongqing, Xi'an of China. The patients suffering from "lower respiratory tract infections" like pneumonia were excluded because we can ...
Study Treatments Patients had to receive the allocated treatment within 1 hour from validation of enrollment criteria. In both groups, the allocated treatment was continued until the patient required endotracheal intubation or (in case of no intubation) up to intensive care unit discharge. In the hi...