especially as result ofβ1–6 Mannose branching, whose synthesis is under control ofGlcNAcT-V[71]. This originates functionally diverseN-glycosidic chains in relevant cancer-associated proteins that are profoundly involved in cancer growth, invasion, metastasis, and immune recognition...
The influence of cell surface glycosylation on innate and adaptive immune responses has been consistently explored in the context of inflammation, autoimmunity and cancer, opening an avenue for the new field of glycoimmunology [15,90]. More recently, several tumour associated glycans have been suggest...
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