Support levels are on the flip side of the coin. Support refers to the price level on achartwhere equilibrium is reached. This means that demand has increased to match supply. This causes the decline in the price of the asset to halt; therefore, the price has reached a floor. As you c...
Checks if an object's property is equal to a value.mapPropDeprecated in favor of lodash update Applies a map function at a specific pathExample:mapProp(double, 'a', {a: 2, b: 1}) -> {a: 4, b: 1}getOrReturn_.get that returns the target object if lookup fails...
And because the on/off current ratio at forward bias is equal to \({\rm{\eta }}\mathrm{kT}/{\rm{e}}{R}_{base}{I}_{0}\), log(on/off) can be expressed as $$\mathrm{log}(on/off)\approx \frac{e}{kT}{\Phi }_{B00}(1-\sqrt{1-\varsigma (t)}),$$ (5) And since...
jejuni) is one of the major causes of bacterial gastroenteritis in both developed and developing countries[1-3]. People become infected by consuming contaminated food, particularly poultry meat, raw milk, and water[4-7]. In addition to gastrointestinal illness, C. jejuni may also lead to ...
While alterations in AKT are associated with acquired resistance to MK-2206, ipatasertib resistance is driven by rewired compensatory activity of parallel signaling pathways. Importantly, MK-2206 resistance can be overcome by treatment with ipatasertib, while ipatasertib resistance can be reversed by...
mRNA is given as ratio of MRP5 mRNA/β-actin relative to an internal standard. Expression levels were statistically not different (Kruskal-Wallis test, Mann-Whitney U-test). Antibodies The AMF antibody was generated against the deduced C-terminal sequence AMFAAAENKVAVKG specific for human MRP5...
(DV)16. These mutations enable PfCRT to efflux CQ out of the DV, thereby preventing CQ from binding to heme and inhibiting its detoxification. Heme is released upon enzymatic proteolysis of host hemoglobin (Hb), yielding globin chains that provide a vital source of amino acids for parasite ...
Understanding how microbial pathogens adapt to treatments, humans and clinical environments is key to infer mechanisms of virulence, transmission and drug resistance. This may help improve therapies and diagnostics for infections with a poor prognosis, s
Antibiotic degrading bacteria can reduce the efficacy of drug treatments by providing antibiotic exposure protection to pathogens. While this has been demonstrated at the ecological timescale, it is unclear how exposure protection might alter and be affe
However, the exact mechanism of drug resistance in EOC cells related to CFL-1 phosphorylation is still unclear. This study aimed to reveal the impact of p-CFL-1 on paclitaxel resistance in EOC cells. We confirmed that SSH-1 regulated the phosphorylation of CFL-1 at Ser-3 to prevent SKOV3...