we performed single-cell RNA sequencing (scRNA-seq) analysis using sorted CD8+T cells from the livers of ND, HFHC, and RES mice, respectively. First, a total of 25,851 cells were clustered into 17 clusters based on the gene signatures (Fig.3a, b). Of interest, ...
our study provides a proof of concept that depletion of GLPMs may reduce local recurrence of liver metastases. Indeed, our findings may provide alternate avenues in the fight against liver metastases and their recurrence by manipulating GLPMs and considering the peritoneal cavity as a portal for mo...
http://ptop.gencat.cat/rpucportal/AppJava/cercaExpedient.do?reqCode=veure&codintExp=68874&fromPage=load (2002) Google Scholar Özdemir and Selçuk, 2017 D. Özdemir, I. Selçuk From pedestrianisation to commercial gentrification: The case of Kadıköy in Istanbul Cities, 65 (2017)...
Among GI tract organs, the liver is a key site of immune surveillance, as it has a large population of resident macrophages and receives the blood drained from the guts through the hepatic portal circulation. Although it is widely accepted that the hepatic tissue is a major target for vagus ...
The article, The Mini Z Resident (Mini ReZ): Psychometric Assessment of a Brief Burnout Reduction Measure, written by Linzer et al., was originally published electronically on the publisher's internet portal on July 22, 2022, without open access. With the author(s)' decision to opt for ...
We searched MEDLINE, CINAHL plus, Cochrane Library, MedEdPortal and Pubmed. Keywords used were internal medicine, training/education/residency, patient/client-centered care, inter-professional/multi-disciplinary/inter-disciplinary and nursing/allied health. Screening of search results was done by the ...
The fundamental mechanism how heterogeneous hepatic macrophage (Mφ) subsets fulfill diverse functions in health and disease has not been elucidated. We recently reported that CCR9+ inflammatory Mφs play a critical role in the course of acute liver inju
Of the 185 remaining actives, 71 compounds have a developmental status (according to National Center for Advancing Translational Sciences [NCATS] portal for drug development information; https://drugs-01.ncats.io/; Table S1C). We focused our efforts on five FDA-approved drugs for further assessme...
All vector-administered macaques had minimal to mild mononuclear cell infiltration within the portal areas (representative images shown in Figure S2); one macaque administered with the low vector dose (RA0721) showed minimal Ito cell hyperplasia. Detection of hUGT1A1co Expression in Rhesus Macaque ...
NATURE COMMUNICATIONS | 8:13839 | DOI: 10.1038/ncomms13839 | www.nature.com/naturecommunications 1 ARTICLE NATURE COMMUNICATIONS | DOI: 10.1038/ncomms13839 The liver is situated in a unique systemic circulation system that receives blood from both the hepatic artery and the portal vein, making ...