Patients with very long-chain acyl-CoA dehydrogenase (VLCAD) and long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD)/mitochondrial trifunctional protein (MTP) deficiency, disorders of the mitochondrial long-chain fatty acid oxidation, can present with hypoketotic hypoglycemia, rhabdomyolysis, and cardiomyop...
WT wild type, vDG ventral dentate gyrus, dDG dorsal dentate gyrus, SERPINA3K serine protease inhibitor A3K, SERPINA3N serine protease inhibitor A3N, ADI1 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, LVD isovaleryl-CoA dehydrogenase, TAGLN transgelin, HDHD3 haloacid dehalogenase-like ...
The antianginal agent trimetazidine does not exert its functional benefit via inhibition of mitochondrial long-chain 3-ketoacyl coenzyme A thiolase. Circ Res. 2003;93(3):e26–32. https://doi.org/10.1161/01.RES.0000086943.72932.71. Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, ...