Another aspect of replacement is the use of “lower” species of animals wherever possible. If we can use a dog instead of a primate and hope to achieve the same quality results, then it must be done. If we can use a rabbit instead of a dog, or a mouse instead of a rabbit, then ...
Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. ...
or the National Research Council'sGuide for the Care and Use of Laboratory Animalsand the authors should clearly indicate in the manuscript that such guidelines have been followed. The sex of animals must be indicated, and where appropriate, the influence (or association) of sex on the results...
Evolutionary genetics articles from across Nature Portfolio Atom RSS Feed Evolutionary genetics is the study of how genetic variation leads to evolutionary change. It includes topics such as the evolution of genome structure, the genetic basis of speciation and adaptation, and genetic change in ...
The tumor volume was estimated using the following formula: (length * width2)/2. The grouping of all the animals was randomized. The experiments were approved by the Animal Experimental Ethical Inspection of the First Affiliated Hospital, Shihezi University. Human samples Formalin-fixed paraffin-...
To do this, we focus on the UK's A(SP)A, which is regulated by a specialised unit within the UK's Home Office: the Animals in Science Regulation Unit (ASRU). To require an A(SP)A licence, an activity must be: (i) performed on a “protected animal”, i.e. living vertebrates ...
ECT is characterized by the fulminant epidemic, high fatality rate and serious harm to the production and scientific research of laboratory animals. This led to a multi-million dollar loss in biomedical research funds [7].Consequently, mousepox is one of the pathogens that must be excluded in ...
All requests to change authorship must be submitted usingthis form. Requests which do not comply with the instructions outlined in the form will not be considered. Only in exceptional circumstances will the journal editor consider the addition, deletion or rearrangement of authors post acceptance. ...
Society is increasingly aware of the connection between the health of the land, of animals and of humans. Visions of ‘foodscapes’ and ‘healthscapes’ are eclipsing the conventional view of landscapes focussed solely on production. Livestock production farming systems must co-evolve with this thin...
Here authors demonstrate a role for nonapoptotic caspase-3 activation in neurons with elevated activity, in the promotion of C1q deposition and synaptic phagocytosis by microglia. Megumi Andoh Natsuki Shinoda Ryuta Koyama ResearchOpen Access22 Jan 2025 Nature Communications Volume: 16, P: 918 ...