Impairing follicle-stimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance Pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone stimulate the gonads by regulating germ cell proliferation and differ...
The hormonal imbalance can create a range of physiological issues, for instance, an imbalance in serotonin will lead to damaging behaviour in chickens, such as cannibalism and pecking [7, 8]. The physiological response in chicken farms is further exacerbated by environmental stresses that raise ...
1,11,12,13 Despite this, extensive preclinical research and clinical studies have been conducted in both male animal models and men, primarily driven by concern about the influence of the hormonal cycle (e.g., menstrual cycle) on outcomes as well as the classification of women as “protected...
Besides hormonal factors, inflammatory mechanisms also have a significant impact on the relationship between fat and osteoporosis [31]. Abdominal visceral adipose tissue contains higher levels of adipokines [32], which increase the number of inflammatory factors and lead to elevated bone resorption and ...
Polycystic ovary syndrome (PCOS), characterized by hormonal imbalance and ovarian dysfunction, often starts during adolescence. Inconsistent diagnostic criteria, variable provider knowledge, and lack of consensus pose specific challenges for the care of women with PCOS. These factors encourage inaccurate dia...
such as hormonal imbalance (Hill et al.2012) or disturbance in microbiome composition (mainly the increase in the proportion of Firmicutes accompanied by the decrease in the proportion of Bacteroidetes) (Suzuki and Worobey2014). Therefore, certain individuals can keep their weight constant despite th...
symptom. People focus on losing weight, when in fact they should tackle the underlying issue of hormonal imbalance caused by high sugar consumption. The connection between hormonal imbalance and fat is not new, and you can read more about it in myprevious articlewhich talks about hormone ...
Historically, the primary focus of cancer research has been molecular and clinical studies of a few essential pathways and genes. Recent years have seen the rapid accumulation of large-scale cancer omics data catalysed by breakthroughs in high-throughput
The exact etiology and pathogenesis of pSS remain unclear, with current evidence suggesting a combination of genetic factors, viral infections, and hormonal abnormalities leading to immune dysfunction [254]. A study identified that a combination of six ferroptosis-related genes, including TBK1, SLC1A4...
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365, 1687–1717 (2005). Article Google Scholar You, Y. N., Rustin, R. B. & Sullivan, J. D. Oncotype DX® colon cancer assay for ...