RT, radiation therapy; Gy, Gray; cc, cubic centimetre; CDK4/6, cyclin-dependent kinase 4 and 6; PARP, poly (ADP-ribose) polymerase; ADC, antibody-drug conjugates; T-DM1, ado-trastuzumab emtansine; CTCAE, Common Terminology Criteria for Adverse Events; PTV, planning target volume. a ...
High Interactivity The Microsoft Internet Explorer browser framework extends the base functionality described in the previous section and offers support for additional usability features such as drag and drop for setting column widths and positions, the ability to select rows and fields by clicking ...
Directed evolution to bypass cyclin requirements for the Cdc28p cyclindependent kinase. Mol. Cell 4:353–363 - Levine, Kiang, et al. - 1999 () Citation Context ...nly required to activate Cdc28, rather than to target the CDK to specific substrates. This hypothesis is further supported by ...
a Volcano plot from label-free microfluidic pull-down for CDK8-GFP bait using 25,000 cells. Dotted gray lines represent statistical cut-offs. Black dots identify significant proteins; red dots are used for known interactors of the bait. ID refers to the total number of proteins reported and ...
This competition is important for adequate spindle length to support meiosis I. We also describe a unique requirement for AURKB to negatively regulate AURKC to prevent aneuploidy. Together, our work reveals oocyte-specific roles for the AURKs in regulating each other’s localization and activity. ...
Solved: Hi We have ECC 6.0 on support package 12. I want to implement enhancement package 3 stack 2 and SAP HR 34. SAP note 1130534 says the requirements for HR sp's
While a/b-tubulin heterodimers can spontaneously polymerize to generate MTs in vitro, MT nucleation in vivo is initiated from a ring-like template of g-tubulin (another member of the tubulin superfamily) that can promote MT nucleation at concentrations below those required for spontaneous assembly1...
High Interactivity The Microsoft Internet Explorer browser framework extends the base functionality described above and offers support for additional usability features such as drag and drop for setting column widths and positions, the ability to select rows and fields by clicking anywhere within the ...
To be enrolled, patients must have received one or two lines of endocrine therapy for advanced or metastatic breast cancer, and have received prior treatment with a CDK4/6 inhibitor in combination with either fulvestrant or an aromatase inhibitor. Patients could have received no more than one lin...
"Software Requirements for Siebel Enterprise Server—Binary Compatibility Support" on page 27 In Table 6 on page 26, added support for IBM AIX 7.1, and moved support for Oracle Solaris 11 from Table 6 on page 26 to Table 7 on page 27, as Oracle Solaris 11 is supported for binary ...