a, Indicated PDOs were treated as indicated for 72 h and analysed for cell viability by ATPlite assay. Synergy graphs were generated with Combenefit (Loewe model).b,c, The growth of PDX-R tumours was assessed in mice treated with: control (saline), cisplatin (2 mg kg−1, once ...
n = 6 for all data. Error bars in all figures in this paper indicate SEM. We overexpressed either wild-type dNR1(wt) or Mg2+-block-site-mutated dNR1(N631Q) transgenes (Figure 2A) in neurons using an elav-GAL4 driver: elav-GAL4/UAS-dNR1(wt), [elav/dNR1(wt)], and elav-GAL...
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