replication of virusesrole of virus particlesvirus attachmentvirus gene expressionDNA virusesreversivirusesmRNA synthesiscapping and polyadenylationThe virus-host relationship describes those interactions which occur when a virus infects a cell. Infection converts the metabolically inert virion into the dynamic...
The replication and transcription process of influenza vRNAs are carried out by NP and the three polymerase subunits, an acidic (PA) and two basic (PB1 and PB2) proteins, which are encoded by the three largest vRNA segments [1]. Unlike many RNA viruses, influenza vir...
www.nature.com/scientificreports OPEN received: 14 December 2015 accepted: 21 June 2016 Published: 12 July 2016 Exploration of acetanilide derivatives of 1-(ω-phenoxyalkyl) uracils as novel inhibitors of Hepatitis C Virus replication Andrea Magri1,2,3, Alexander A. Ozerov4, Vera L....
A natural reservoir of influenza B viruses outside humans has not been identified and thus, these viruses are considered to be exclusively human pathogens. Although both influenza A and B viruses have caused widespread human epidemics in the past, the genetic determinants of the virulence and ...
Similarly, lycorine has been reported can inhibit the replication of multiple types of viruses, such as influenza virus, West Nile virus, and dengue virus, but most of these studies are limited to in vitro experiments [[44], [45], [46]]. In our previous studies, we first confirmed the ...
Importantly, this effect is only stimulated by RNA viruses or intracellular RNA (Zhang et al., 2019). Our results showed that H1N1 infection activated the MAVS/RIG-I signaling pathway and that the MAVS and RIG-I protein levels increased gradually in a time-dependent manner after H1N1 infection...
Currently, there is no single source that permits comparison of the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our particular system, missing out on the opportunity ...
(1978). in: Oncogenesis and Herpes-viruses III, pp. 63–73. Ben-Porat, T, Kaplan, AS (1962) Virology 16: pp. 261-266 CrossRef Ben-Porat, T, Kaplan, AS, Stehn, B, Rubenstein, AS (1976) Virology 69: pp. 547-560 CrossRef Ben-Porat, T., Ladin, B., and Veach, R. A...
The present invention relates generally to the fields of oncology, virology and immunotherapy. More particularly, it concerns the use of poxviruses, specifically the replication com
Abstract poster session III respiratory viruses, hepadnaviruses, togaviruses, othersAdenovirus type 5 replication is inhibited by S-HPMPC in the NZ rabbit ocular model : YJ Gordon, E Romanowski, T Araullo-Cruz & E de Clercq∗, The Eye & Ear Institute of Pittsburgh, USA, ∗ Rega ...