Major cartilaginous defects of the femoral condyles of the knee joint, caused by chondropathy and chondral trauma can be a precursor to osteoarthritis.Particularly in cases with large defects the therapy often remains unsuccessful. Even the substitution of articular hyaline cartilage by autogenous ...
The aim of this work was evaluation of the kinetics of the release of a steroidal anti-inflammatory preparation (SAP) from implants that are replacing the cruciate ligaments of the knee. The influence of a deposition technique on the kinetic parameters of the drug release from the polymeric syst...