This familial disease may represent congenital renal wasting of magnesium and potassium.doi:10.1111/j.1442-200X.1993.tb03047.xFUJIHIKO IWATADepartment of Pediatrics, Tobu Regional Hospital, Tokyo, JapanYOSHIO HANAWADepartment of Pediatrics, Tobu Regional Hospital, Tokyo, JapanHIROTADA TAKASHIMA...
Sebastian A, McSherry E, Morris Jr RC. On the mechanism of renal potassium wasting in renal tubular acidosis associated with the Fanconi syndrome (type 2 RTA). J Clin Invest. 1971;50(1):231–43. CASPubMed CentralPubMedGoogle Scholar Baum M. The cellular basis of Fanconi syndrome. Hosp ...
< 5.5 if serum HCO3– is ≤ proximal tubule reabsorption threshold Untreated and at steady state No urinary HCO3– wasting is occurring Mixed ( type 3 ): variable Hyperkalemic ( type 4 ): < 5.5Serum potassium :Distal ( type 1 ): low Proximal ( type 2 ): low Hyperkalemic ( type...
K+wasting associated withBartter syndrome.15,16,17,18Moreover, disease resulting from inactivation ofNCCand the ClCchloride channelbeta subunitbarttin, anddiureticssuch asthiazideinhibitors of the NCC co-transporter that decrease NaCl reabsorption in the DCT, also cause renal K+wasting by this common...
Because of the tight coupling between sodium reabsorption and potassium secretion at the CCD, the use of loop or thiazide diuretics is clinically associated with hypokalemia, whereas amiloride intervention causes hyperkalemia. Bartter’s syndrome, characterized by renal salt wasting and polyuria-associated...
High facility-level serum potassium variability associated with mortality in hemodialysis patients: results from Chinese Dialysis Outcomes and Practice Patterns Study (DOPPS) Xinju Zhao, Fan Fan Hou, Xinling Liang, Zhaohui Ni, Xiaonong Chen, Yuqing Chen, Liangying Gan & Li Zuo Article: 2211157 Pub...
Renal tubular acidosis (RTA) arises when the kidneys either fail to excrete sufficient acid, or are unable to conserve bicarbonate, with both circumstances leading to metabolic acidosis of varying severity with altered serum potassium. Proximal and distal types of RTA can be differentiated according ...
Diuretics increase the rate of urine flow and sodium excretion and are used to adjust the volume and/or composition of body fluids in a variety of clinical situations, including hypertension, heart failure, renal failure, nephrotic syndrome, and cirrhosis. The objective of this chapter is to prov...
(A) NaCl is reabsorbed through a concerted action of the Na+-K+-2Cl− cotransporter (NKCC2), the renal outer medullary potassium channel (ROMK) and basolateral Cl− channel (ClC- mice showed significantly reduced plasma Mg2+ levels, increased urinary excretion of Mg2+ and Ca2+ and ...
Almost invariably, severely burned patients require exogenous potassium because of the heightened aldosterone response, which results in potassium wasting; therefore, hyperkalemia is rare even with some renal insufficiency. Intermittent dialysis remains a viable replacement therapy for severe ARF in the ...