Allocation to simvastatin therapy was not associated with excess risk for abnormal liver function test results or elevated creatine kinase levels. Conclusion: During a 1-year treatment period, simvastatin, 20 mg/d, produced a sustained reduction of approximately one quarter in low-density ...
Chronic kidney disease, worsening renal function and outcomes in a heart failure community setting: A UK national studyHeart failureChronic kidney diseaseWorsening renal functionComorbidityHospitalisationDeathPopulation basedBackground: Routine heart failure (HF) monitoring and management is in the community ...
As with other organs and systems in the human body, urine biochemical analysis is the most basic test for the routine examination of urinary system function. The results of the urine analysis showed that no RBC, WBC, glucose, proteins, or hematuria were detected in the urine of female or ...
Feline morbillivirus (FeMV) is a newly discovered paramyxovirus infecting domestic cats and its role in the pathogenesis of feline chronic kidney disease (CKD) has been suggested, however not confirmed. The primary aim of the study was to evaluate the re
Rapid progression (RP), an abnormally rapid deterioration in renal function, is a term commonly used in the renal literature. However, unlike CKD (typically defined as two consecutive eGFRs ≤60 ml/min/1.73 m2 measured more than 3 months apart), it is without a standardised definition. It ...
Split renal function tests by means of single catheter techn i que were performed under urea diuresis and ADH-urea loading. The subjects studied consisted of 7 patients with unilateral atrophic pyelonephritis, of whom 2 with hypertension and 5 without hypertension (2 males and 5 females with the...
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identity and function17,18. Moreover, master TFs participate in interconnected auto-regulatory circuitries or “cliques” that are self-reinforcing, show marked cell selectivity, and function to maintain cell state and/or cell survival17,19. In addition, analyses of population-based epigenomes have...
“ComBat” function, a popular batch correction algorithm, to eliminate the batch effect. This process ensured that any system-specific variations between the two datasets were effectively removed, resulting in a more robust and reliable dataset for downstream analysis [28]. To identify the MRGs ...
At the beginning of each experiment, arteries were challenged twice with 120 mM K+ (KPSS) in order to test vessel viability. Concentration-responses curves to the endothelial agonist acetylcholine (ACh) and to the β-adrenergic agonist isoprenaline were performed to assess arterial function on arter...