C., Howe, A. K., & Badger, G. J. (Janeiro de 2013). Cytoskeletal remodeling of connective tissue fibroblasts in response to static stretch is dependent on matrix material properties. Journal of cellular physiology, 228(1), 50-57. doi:doi:10.1002/jcp.24102...
Connective tissue remodeling is achieved by a complex process involving several cell types, a plethora of growth factors, cytokines, chemokines and turnover of extracellular matrix (ECM). The main enzymes that degrade ECM molecules are matrix metalloproteinases (MMPs) and their activities are regulated...
It has been used to dye the connective tissue around an ulcer or nonpenetrating, linear incision in the rabbit cornea and sclera, and the healing of the tissue has been examined up to 1 yr later. Sagittal sections were stained for light microscopy, and adjacent unstained sections were ...
Matrix metalloproteinases and their inhibitors in connective tissue remodeling. Patterns of left ventricular hypertrophy and geometric remodeling in essential hypertension. VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation ...
Previous study showed Endo180 was involved in re-epithelialization and connective tissue remodeling during wound repair process [27]. Moreover, Endo180 could directly bind to collagen and help collagen degraded in the lysosome during ECM remodeling [9]. Our findings align with the previous studies,...
Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development Coordinated production and remodeling of the extracellular matrix is essential during development. It is of particular importance for skeletogenesis, as th... Ivkovic,S. - 《Development》 被引量: 1516发表...
Connective Tissue Growth Factor (CTGF) has been associated with tissue remodeling and is highly expressed in failing hearts. Our aim was to test if inhibition of CTGF would alter the course of cardiac remodeling and preserve cardiac function in the protein kinase Cε (PKCε) ...
Loss of connective tissue growth factor expression promotes remodeling of the extracellular matrix and epithelial-to-mesenchymal transition in ovarian cancer (2294) doi:10.1016/j.ygyno.2023.06.412Gynecologic OncologyAyesha AlveroRadhika GogoiSandra GaloforoColton MorrisYuan YouHarry RamosAlexandra FoxRoslyn ...
The past two decades reveal a growing role of continuum biomechanics in understanding homeostasis, adaptation, and disease progression in soft tissues. In this paper, we briefly review the two primary theoretical approaches for describing mechano-regulated soft tissue growth and remodeling on the continu...
The cervix serves as a protective barrier from invading microorganisms and as a structural barrier to delivery of the fetus. Among all biological processes, the phenomenal connective tissue remodeling that occurs in the cervix during and after parturition is unparalleled in scope and magnitude. The pr...