Here, we use this now-accessible approach to directly increase synaptic 5-HT in humans, examining its influence on domains of behaviour historically considered core functions of serotonin: aversive processing, behavioural inhibition, and memory. In line with our hypothesis that fenfluramine would resul...
Sustained release nifedipine (20 to 80 mg/day) has produced statistically significant blood pressure reductions of about 20% in patients with essential hypertension in noncomparative as well as in placebo-controlled trials. Generally, response rates (usually the percentage of patients attaining a goal ...
In terms of their interaction with biological fluids, nanosystems tend to be stable (no degradation and/or dissolution in blood). Non-biodegradability is relative to the time scale associated with the drug release process. In fact, many studies of nanocarriers revealed that the encapsulated drug ...
could be retained by an externally applied magnetic field, enhancing the specific accumulation of the cargo in the target tissue. In order to be able to circulate through the blood vessels, the membranes should be,...
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Therefore, in this case, the Cu release was also slowed down by a mixed layer of Ti and Cu. The different Cu release of top-layer and bottom-layer is also discussed by Stranak et al. in relation to their different morphology. However, they did not take into account the different Cu ...