产品参数【产品介绍】Relaxin 3 receptor 1又名GPCR135 是一种由469个氨基酸组成的跨膜糖蛋白,是GPCR1(G-protein coupled receptor 1)家族成员之一。 该蛋白主要分布于脑组织和脊髓中,当它与其胚体Relaxin 3结合后会抑制cAMP的蓄积。 【免疫原】免疫原为KLH-多肽交联物。
Protein Name:Relaxin-3 receptor 1 Human Gene Id:51289 Swiss-Prot:Q9NSD7 Formulation:Liquid in PBS containing 50% glycerol, 05% BSA and 002% sodium azide Source:Rabbit Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen ...
Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and has also been identified for binding specifically to the LGR7 receptor, previously identified as an “orphan” G protein-coupled receptor. ...
Relaxin family peptide receptor 1 (RXFP1) and RXFP3 are expressed in the rat hypothalamic paraventricular nucleus (PVN). Corticotropin-releasing factor (CRF) is produced in the PVN in response to stressors and promotes adrenocorticotropic hormone secretion from the anterior pituitary. We hypothesized ...
ReliaTech全称为受体配体技术有限公司 (Receptor Ligand Technologies GmbH),1999年成立,总部位于德国不伦瑞克,是一家后基因组生物技术公司。ReliaTech主要专注于受体和配体的发现与研究。此外,ReliaTech也开发应用于血管与淋巴管生成研究的相关高品质试剂。目前ReliaTech提供近2800款产品,产品线主要包括重组蛋白(细胞因子、生...
Relaxin-3 is a secreted protein structurally related to insulin that is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and has ...
Relaxin-3 (H3 relaxin, Insulin-like peptide-7, INSL7) is a secreted protein structurally related to insulin, which is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or...
Relaxin-3 is a secreted protein structurally related to insulin that is expressed primarily in the brain and central nervous system. Relaxin-3 has been identified as the ligand for the GPCR135 receptor, previously known as “somatostatin-like” or “angiotensin-like” peptide receptor, and has al...
(2012) Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies. Amino Acids 43 , 983-992 Online publication date: 1-Aug-2012. /Zhang W-J, Luo X, Liu Y-L, Shao X-X, Wade JD, Bathgate RAD, Guo Z-Y (2012) Site-specific DOTA/...
(RXFP1) receptor, but with lower affinity than that of Relaxin-2 (1, 7). Although binding of Relaxin-3 to LGR7 increases intracellular cAMP, binding to GPCR135 inhibits cAMP accumulation, indicating coupling to Gi, Go or Gz by this receptor (1, 5). Relaxin-3 expression does not ...