The relaxin signaling pathway refers to all proteins involved in the pathway of relaxin signaling pathway and related regulatory factors. Relaxin is a peptide hormone that relaxes the birth canal before delivery. Mainly produced in the corpus luteum of the ovary during mammalian pregnancy, it relaxes...
RelaxinGastrointestinalmotilitySmoothmuscleAC/cAMPGC/cGMPAIM To investigate the signaling pathways involved in the relaxin(RLX) effects on ileal preparations from mice through mechanical and electrophysiological experiments.METHODS For mechanical experiments, ileal preparations from female mice were mounted in or...
Relaxin inhibits renal myofibroblast differentiation via RXFP1, the nitric oxide pathway, and Smad2 The hormone relaxin inhibits renal myofibroblast differentiation by interfering with TGF-beta1/Smad2 signaling. However, the pathways involved in the relax... I Mookerjee,TD Hewitson,ML Halls,... - ...
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AIM To investigate the signaling pathways involved in the relaxin(RLX) effects on ileal preparations from mice through mechanical and electrophysiological experiments.METHODS For mechanical experiments, ileal preparations from female mice were mounted in organ baths containing Krebs-Henseleit solution. The ...
International Journal of Molecular Sciences Article Relaxin 2/RXFP1 Signaling Induces Cell Invasion via the β-Catenin Pathway in Endometrial Cancer Misaki Fue 1, Yasuhiro Miki 1,* ID , Kiyoshi Takagi 2, Chiaki Hashimoto 3, Nobuo Yaegashi 3, Takashi Suzuki 2 and Kiyoshi Ito 1 1 Department of...
signaling. However, the role of CTRP1, CTRP6 and CTRP8 at the ocular surface remains unclear. In this study, we investigated the effects of CTRP1, CTRP6, and CTRP8 on epithelial ocular surface wound closure and their dependence on the RXFP1 receptor pathway. CTRP1, CTRP6, and CTRP8...