Meiosis is distinguished from mitosis by the way double-strand breaks are made and by the synapsis and segregation of homologous chromosomes. Recent studies with the yeast Saccharomyces cerevisiae have identified some of the key players that link homologous recombination to synaptonemal complex formation....
et al. Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res. 21, 447–455 (2011). Article Google Scholar Li, H., Quang, D. & Guan, Y. Anchor: trans-cell type prediction of transcription factor binding sites. Genome Res. 29, ...
In hybrids between species of Hordeum and Leymus there was a clear differentiation between the H genomes of Hordeum species and the genomes of Leymus species after probing with genomic Hordeum or Leymus DNA. Chromosomes of species of Leymus and Psathyrostachys were also differentiated by sub...
Chapter 12 - Evolutionary Relationships Among Diverse Bacteriophages and Prophages: All The World's a Phage We report DNA and predicted protein sequence similarities, implying homology, among genes of double-stranded DNA (dsDNA) bacteriophages and prophages spann... RN Burns - Elsevier Ltd 被引量:...
This study was conducted to determine whether the major nasal airway ion transport abnormalities in cystic fibrosis (that is, defective cAMP regulated chloride secretion and basal sodium hyperabsorption) are related to the clinical expression of cystic fibrosis and/or to the genotype. Nasal potential ...
we performed genomic analyses on the initial DCIS lesion and paired invasive recurrent tumors in 95 patients together with single-cell DNA sequencing in a subset of cases. Our data show that in 75% of cases the invasive recurrence was clonally related to the initial DCIS, suggesting that tumor...
DNA is not necessary or sufficient for centromere function, leading to the suggestion that most centromeres are epigenetically regulated (Allshire & Karpen2008). One exception described is that of the point monocentromeres inSaccharomyces cerevisiae, as mutations in CDEIII cause centromere and ...
Indeed, it has been proposed that after WGD, duplicated genes can either accumulate loss-of-function mutations and are functionally lost (non-functionalization [3, 4]) or acquire a new function (neo-functionalization), or split the ancestral function between the paralogs (sub-functionalization) [...
Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells. Blood 122, 2823–2836 (2013). Article CAS Google Scholar Djuretic, I. M. et al. Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper...
Variation in the distribution of a genome-specific DNA sequence on chromosomes reveals evolutionary relationships in the Triticum and Aegilops complex The present study analyzed the distribution pattern of the Ae. speltoides鈥攄erived repetitive clone pGc1R-1 in the Triticum/Aegilops complex. Fluorescence...