pKa and pH - The fundamental distinction between pKa and pH is that pKa denotes an acid's dissociation, whereas pH denotes a system's acidity or alkalinity.
pKa - The pKa value is the negative base -10 logarithm of the acid dissociation constant (Ka) of a solution. The quantitative behavior of acids and bases in solution can be understood only if their pKa values are known. To learn more about Calculation o
Four substitutedcisandtrans-4,5-dihydroxyhexahydropyridazines that were expected to undergo pH induced conformational switching were synthesized and carefully investigated by NMR analyses and calculations. For two of the compounds a large difference in pKaexisted between the two possible chair conformers ...
Which of the following heterocyclics has the lowest pKa value? If H2O has a pKa value of 15.7 and HF has a pKa value of 3.2, which is a stronger base: OH- or F-? Explain. Given the following pKa values, which is the weakest acid? a. HNO2 (pKa = 3.37) b. HF (pKa = 3.45)...
S Hoeller,A Sperger,C Valenta - 《International Journal of Pharmaceutics》 被引量: 122发表: 2009年 Preformulation Study of Saquinavir: pH-Dependent Solubility, Ionization and Partition Coefficients Solubility, pKa and octanol-water partition coefficient were determined by UV spectrophotometry in different...
pH sensorsThe permselectivity of Pt/polyphenols has been investigated. The selective permeability is found to be different for various polyphenols. Relationships of the diffusion rates, the limiting currents for the reduction of H+ ions and the pKa values of the polyphenols have been established. ...
The antioxidant activities of 18 typical phenolic acids were investigated using 2, 2′-diphenyl-1-picrylhydrazyl (DPPH) and ferric ion reducing antioxidant power (FRAP) assays. Five thermodynamic parameters involving hydrogen atom transfer (HAT), single-electron transfer followed by proton transfer (SET...
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Adolescents and young adults (AYA) with cancer face unique psychosocial challenges that often impact their outcomes, including self-rated health. To date, few studies have focused on AYA cancer survivors’ multidimensional unmet needs of cancer care in relation to their health status. Methods/Procedur...
albicans, cancel the proton gradient in the inner membrane, and inhibit ATP synthesis. A decrease in intracellular ATP leads to a reduction of cAMP in a cell [4]. It is known that dimorphism is controlled via the cAMP-PKA pathways [5, 6]. The inhibition of hyphal growth by valinomycin ...