We also included a question on frequency of teeth brushing (< every second day, every second day, once daily, >once daily), as higher family socioeconomic status is associated with greater odds of teeth brushing twice a day or more [18]. As a measure of rural living, place of residence...
Genes associated with both DEmRNAs and WGCNA were intersected for feature selection. To choose the most distinguishable gene signature (hereafter termed core genes), LASSO regression, SVM-RFE, and random forest methods with ten-fold cross-validation were used. These processes were conducted with R...
The SenMayo senescence-associated gene list-derived signature remained significant when paired with lymph node status (p for nodal status = 4.0e-07), estrogen receptor status (p for ESR status = 3.1e-07), HER2 status (p for HER2 status = 0.0031), and size (p for size ...
Ossa DF, Briggs A, Cowell W, Littlewood T, Sculpher M. Utility associated with severity of cancer-related anaemia (CRA): a societal valuation. Value Health. 2004;7(6):680.Ossa D, Briggs A, Cowell W, Littlewood T, Sculpher M. Utility associated with severity of cancer-related anaemia ...
showed that, besides age, tumor stage and comorbidity, better mental health and physical function were associated with lower 10-year mortality [24]. However, these findings should be interpreted with caution. Overall survival, and composite endpoints including survival such as disease-free survival, ...
Intravenous injection of young sEVs into aged mice extends their lifespan, mitigates senescent phenotypes and ameliorates age-associated functional declines in multiple tissues. Quantitative proteomic analyses identified substantial alterations in the proteomes of aged tissues after young sEV treatment, and ...
ventral striatum might be associated with speeding propensity. However, because sports cars are also a cultural icon signalling wealth and social dominance, Erket al.3concluded that the ventral striatum activation they observed in response to images of sports car may be likely to reflect brain ...
Therefore, a secondary model (a recessive risk-associated allele model) was tested comparing homozygotes for the risk-associated allele against other genotypes (AA vs GA + GG) using a 2-sample t test. Results are presented based on this analysis. For both emotional tasks, the ROI was ...
Effects of young sEVs on senescent phenotypes One of the most well-characterized contributors to aging is senescent cells2. We determined the alteration of senescence-associated phenotypes in aged mice after young sEV injection. Senescent cells usually switch on the expression of acidic β-galactosidas...
Ferroptosis, a therapeutic strategy for tumours, is a regulated cell death characterised by the increased accumulation of iron-dependent lipid peroxides (LPO). Tumour-associated long non-coding RNAs (lncRNAs), when combined with traditional anti-cancer medicines or radiotherapy, can improve efficacy and...