More importantly, recent studies also revealed that ALA can influence the inflammatory process by regulating gut microbiota [54,55,56]. Nevertheless, there is no report on the regulatory effect of ALA on inflammation caused by T. gondii infection. Our present results suggest that gut microbiota-...
Additionally, studies investigating the long-term impact of MSC treatment on gut flora composition and function will provide more insight into the therapeutic potential of MSCs in aging-related disorders. Although MSCs are known to migrate to sites of inflammation in various studies, there is a ...
Obesity and related factors have been implicated as possible aetiological factors for the development of glioma in epidemiological observation studies. We used genetic markers in a Mendelian randomisation framework to examine whether obesity-related traits influence glioma risk. This methodology reduces bias...
Stem cell populations in all multicellular organisms are situated in a niche, which is a special microenvironment that defines stem cell fate. The interplay between stem cells and their niches is crucial for stem cell maintenance. Here, we show that an e
Recently I was asked to be the alumni speaker at the Jepson School of Leadership Studies’ Senior Banquet at the University of Richmond. Did I think I was old enough or wise enough to be the alumni speaker? Absolutely not. Did I go and give the speech anyway? You bet. I did, however...
Indeed, a number of studies have demonstrated efficient expression of transgenes using AAV serotype 9 in the mouse retina32,33,34,35. In our previous study, we also showed that Cas9 derived from Campylobacter jejuni is efficiently expressed in the retina and RPE cells after intravitreal injection...
However, future in depth nuclear magnetic resonance (NMR) or co-crystallization studies will be required to experimentally prove the predicted in silico models. Taken together, our study identified a novel positive regulator of PPARγ based on (i) inhibition of ERK1/2 signalling and (ii) direct...
For problem Internet and gaming addictions, other research has been undertaken this decade and provided evidence about other potential behavioural addictions which could be classed into this spectrum of online addiction problems [27]. However, the existing theoretical studies (e.g., critiques, reviews...
Media 2021, 2 104 is less concerned about the thematic issues of fake news. However, both typologies suggest that fake news is closely related to rumor, misinformation, or disinformation (for more insights, see Duffy et al. 2019). A few studies present thematic typologies of fake news that ...