只有富电子的苯酚化合物可以发生该反应，原因是羟基（实际为氧负）与苯环p-π共轭，增加了苯环邻对位的电子云密度；反应的实质是亲电芳香取代反应；反应过程：1、二氯卡宾生成；三氯甲烷脱质子，然后α消除形成二氯碳苯，该反应能发生的原因在于pKa规则，氢氧根共轭酸的酸性更弱；2、苯酚被去质子，成醌型，α位和生...
5、质子淬灭得到产物; 因为给电子共轭效应,苯酚的对位同样可以发生上述的反应,机理类似。有兴趣的可以自己画画,此处不再描述; 学习机理不能认死理,要明白一些事:
Castillo R, Moliner V, Andrés J (2000) A theoretical study on the molecular mechanism for the normal Reimer–Tiemann reaction. Chem P Lett 318:270–275R. Castillo, V. Moliner, J. Andres, A theoretical study on the molecular mechanism for the normal Reimer-Tiemann reaction, Chem. Phys. ...
瑞穆尔-悌曼反应(Reimer-Tiemann Reaction) 概要 在氯仿与碱存在的条件下,在苯酚上导入甲酰基的反应。一般情况的话,主要生成邻位取代产物。 基本文献 ・Reimer, K.; Tiemann, F.Ber.1876,9, 824, 1268, 1285. ・Wynberg, H.Chem. Rev.1960,60, 169. DOI:10.1021/cr60204a003 ・Wynberg, H.; Mei...
Reimer Tiemann reaction 赖悌二氏反应 Reimer's reflex 赖默氏反射 reaction to 对…的反应 the reaction to 对……的反应 reaction stage reaction step 反应阶段 acid reaction n. 酸性反应 allergic reaction 过敏反应 reaction engine n. 喷气发动机 reverse reaction n. 逆反应 cachexia reaction ...
Reimer-Tiemann reaction noun ˈrīmə(r)¦tēmən-, -ēˌmän- :either of two similar chemical reactions: a :a reaction for producing phenolic aldehydes by the action of chloroform and caustic alkali on phenols b :a reaction for producing phenolic acids from carbon tetrachloride, alka...
Chemical Properties || Reimer Tiemann Reaction || Kolbe Reaction View Solution Dehydration Of Alcohols|Reactions Of Phenols |Halogenation|Kolbe's Reaction|Reimer-Tiemann Reaction|Summary View Solution Reaction OF Phenol (Nitration ,Halogenation, Kolbe ,Reimer Tiemann Reaction Etc) || Physical Properties ...
Reimer-Tiemann reaction 网络 Reimer-Tiemann反应; 用氯仿甲酰化
A. V. GAONKARDep. Chem., Goa Univ., Bambolim, Goa 403 005, IndiaJ. K. KIRTANYDep. Chem., Goa Univ., Bambolim, Goa 403 005, IndiaJohn Wiley & Sons, Ltd.CheminformGaonkar AV, Kirtany JK (1991) Reimer-Tiemann reaction using carbon tetrachloride. Indian J Chem Sect B 30B:800...
The Reimer–Tiemann reaction, an aromatic substitution reaction that occurs under basic conditions, is in many respects a unique reaction. It is one of the few organic reactions whose industrial importance seems to increase yearly, notwithstanding the environmental hazards associated with the use of ch...