J. Ventricular zone expressed PH domain containing 1 (VEPH1): an adaptor protein capable of modulating multiple signaling transduction pathways during normal and pathological development. Cell Commun. Signal. 17, 116 (2019). Article Google Scholar Derrien, A. & Druey, K. M. RGS16 function ...
The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. Reprints and permissions About this article Cite this article Zhou, T., Xing, Q....
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Like the CDS, when a smaller base pair span was used, similar conformations were maintained, but as individual hairpins and small multi-branch loops rather than one large domain. Here, the predominant changes were seen downstream of the low z-score structures (Supplementary Figure S14). ...
The topological domains (TADs) from both cell types were shown to indicate genomic neighbourhood of stronger within-domain interactions. The heatmap values indicated in a color scale correspond to the number of times that reads in two 20 kb bins were sequenced as a pair, with the red color ...
Step 2: Integrate data of the same subtype into an expression matrix and replace file names.There are multiple compressed files for each subtype of data, so we integrate the data of each subtype into a matrix and replace the file name with the sample number. Step 3: Delete non-gene count...
Synovial fibroblasts (SFs) are specialized cells of the synovium that provide nutrients and lubricants for the proper function of diarthrodial joints. Recent evidence appreciates the contribution of SF heterogeneity in arthritic pathologies. However, the
The regulatory profile RP([Math Processing Error]x→) = (f (x1),..., f (x N )) of TF x is defined as a sigmoid function, which is justified by some previous studies [55–57] [Math Processing Error]f(xi)=11+e−(xi−x¯)/s)i=1,2,⋯,N where [Math Processing Error]...
demarcated within.bOn theleft, NR2C2 and RXRB motif logos and motif prediction in negative orientationN. brichardi sws1gene promoter (red box) and variant inM. zebra sws1gene promoter (red arrow). On theright, NR2C2 and RXRB partial protein alignment showing DNA-binding domain (DBD) ...
In addition to the above seven known heat-responsive TFs, five novel heat-responsive TFs (Rox1, Cst6, Ume6, Ste12 and Dig1) have also been identified by HIMIA. Rox1 contains a high-mobility group (HMG) domain that is responsible for DNA bending activity [29]. Cst6 and Ume6 regula...